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The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular or single-celled organism. The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus. The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged. During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur. The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles. The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: removal of nonhomologous ends
Acc: GO:0000735
Aspect: Biological Process
Desc: The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 9 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000735 - removal of nonhomologous ends (interactive image map)
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