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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • FUN12
  • mitochondrion
  • translational initiation
  • translation initiation factor activity
  • GTPase activity
  • MAK5
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    90S preribosome 9.1004E-7 8 17 3 6292
    preribosome 7.9274E-6 8 34 3 6292
    cytosolic small ribosomal subunit 1.1149E-5 8 38 3 6292
    small ribosomal subunit 8.0492E-5 8 73 3 6292
    ribonucleoprotein complex 1.6235E-4 8 514 5 6292
    cytosolic ribosome 2.1208E-4 8 101 3 6292
    non-membrane-bounded organelle 2.6233E-4 8 959 6 6292
    intracellular non-membrane-bounded organelle 2.6233E-4 8 959 6 6292
    cytosolic part 3.71E-4 8 122 3 6292
    ribosomal subunit 1.2169E-3 8 183 3 6292
    nucleolus 1.8378E-3 8 211 3 6292
    small nucleolar ribonucleoprotein complex 3.4584E-3 8 72 2 6292
    cytosol 4.3023E-3 8 284 3 6292
    ribosome 4.565E-3 8 290 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    rRNA processing 1.7189E-7 8 128 5 6292
    rRNA metabolic process 2.4182E-7 8 137 5 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.8367E-7 8 13 3 6292
    maturation of SSU-rRNA 4.7479E-7 8 59 4 6292
    ribosome biogenesis 6.7573E-7 8 346 6 6292
    ribonucleoprotein complex biogenesis 1.0727E-6 8 374 6 6292
    ncRNA processing 2.291E-6 8 215 5 6292
    gene expression 2.9372E-6 8 1283 8 6292
    ncRNA metabolic process 5.5383E-6 8 257 5 6292
    ribosomal subunit assembly 3.4321E-5 8 55 3 6292
    translation 3.5782E-5 8 376 5 6292
    RNA processing 3.7674E-5 8 380 5 6292
    regulation of translation 3.8233E-5 8 57 3 6292
    cellular component biogenesis 4.0619E-5 8 694 6 6292
    posttranscriptional regulation of gene expression 4.6914E-5 8 61 3 6292
    ribosome assembly 5.4212E-5 8 64 3 6292
    regulation of cellular protein metabolic process 6.5054E-5 8 68 3 6292
    organelle assembly 6.797E-5 8 69 3 6292
    regulation of protein metabolic process 8.3843E-5 8 74 3 6292
    ribonucleoprotein complex assembly 1.6068E-4 8 92 3 6292
    cellular macromolecule metabolic process 3.0018E-4 8 2285 8 6292
    macromolecule metabolic process 3.7455E-4 8 2349 8 6292
    ribosomal large subunit assembly 1.1316E-3 8 41 2 6292
    cellular macromolecular complex assembly 1.1976E-3 8 182 3 6292
    primary metabolic process 2.0036E-3 8 2896 8 6292
    ribosomal large subunit biogenesis 2.8269E-3 8 65 2 6292
    cellular metabolic process 2.9013E-3 8 3033 8 6292
    RNA metabolic process 2.9766E-3 8 954 5 6292
    cellular macromolecular complex subunit organization 3.31E-3 8 259 3 6292
    metabolic process 3.9991E-3 8 3157 8 6292
    macromolecular complex assembly 4.1746E-3 8 281 3 6292
    cellular protein metabolic process 5.103E-3 8 1074 5 6292
    protein metabolic process 6.5695E-3 8 1136 5 6292
    cellular macromolecule biosynthetic process 7.9943E-3 8 1187 5 6292
    macromolecule biosynthetic process 8.0545E-3 8 1189 5 6292
    macromolecular complex subunit organization 8.1895E-3 8 357 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 7.8854E-5 8 212 4 6292
    rRNA binding 1.6826E-4 8 16 2 6292
    structural molecule activity 4.8751E-4 8 339 4 6292
    nucleic acid binding 5.58E-4 8 666 5 6292
    RNA binding 6.6069E-4 8 367 4 6292
    RNA helicase activity 1.1875E-3 8 42 2 6292
    helicase activity 4.5722E-3 8 83 2 6292
    nucleoside-triphosphatase activity 6.5162E-3 8 329 3 6292
    hydrolase activity, acting on acid anhydrides 7.936E-3 8 353 3 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 7.936E-3 8 353 3 6292
    pyrophosphatase activity 7.936E-3 8 353 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle