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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
FUN12
  • mitochondrion
  • translational initiation
  • translation initiation factor activity
  • GTPase activity
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL4B
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • STM1
  • cytoplasm
  • nuclear telomere cap complex
  • anti-apoptosis
  • telomere maintenance
  • DNA binding
  • telomeric DNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    preribosome 1.531E-9 11 34 5 6292
    90S preribosome 1.1899E-8 11 17 4 6292
    cytosolic small ribosomal subunit 3.622E-7 11 38 4 6292
    cytosolic ribosome 4.1304E-7 11 101 5 6292
    cytosolic part 1.0628E-6 11 122 5 6292
    small ribosomal subunit 5.1761E-6 11 73 4 6292
    ribonucleoprotein complex 5.7599E-6 11 514 7 6292
    ribosomal subunit 7.8993E-6 11 183 5 6292
    cytosol 6.6782E-5 11 284 5 6292
    ribosome 7.3831E-5 11 290 5 6292
    non-membrane-bounded organelle 3.5121E-4 11 959 7 6292
    intracellular non-membrane-bounded organelle 3.5121E-4 11 959 7 6292
    macromolecular complex 1.5504E-3 11 1635 8 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 4.3817E-10 11 376 9 6292
    gene expression 1.0844E-6 11 1283 10 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.1264E-6 11 13 3 6292
    cellular protein metabolic process 4.7266E-6 11 1074 9 6292
    protein metabolic process 7.6839E-6 11 1136 9 6292
    cellular macromolecule biosynthetic process 1.1227E-5 11 1187 9 6292
    macromolecule biosynthetic process 1.1391E-5 11 1189 9 6292
    cellular macromolecule metabolic process 1.4269E-5 11 2285 11 6292
    macromolecule metabolic process 1.9349E-5 11 2349 11 6292
    regulation of translation 1.1049E-4 11 57 3 6292
    cellular biosynthetic process 1.2033E-4 11 1567 9 6292
    maturation of SSU-rRNA 1.2253E-4 11 59 3 6292
    posttranscriptional regulation of gene expression 1.3539E-4 11 61 3 6292
    biosynthetic process 1.4499E-4 11 1602 9 6292
    regulation of cellular protein metabolic process 1.8726E-4 11 68 3 6292
    primary metabolic process 1.9438E-4 11 2896 11 6292
    regulation of protein metabolic process 2.4083E-4 11 74 3 6292
    cellular metabolic process 3.2347E-4 11 3033 11 6292
    metabolic process 5.03E-4 11 3157 11 6292
    rRNA processing 1.2042E-3 11 128 3 6292
    rRNA metabolic process 1.466E-3 11 137 3 6292
    negative regulation of programmed cell death 1.7483E-3 11 1 1 6292
    anti-apoptosis 1.7483E-3 11 1 1 6292
    negative regulation of cell death 1.7483E-3 11 1 1 6292
    negative regulation of apoptosis 1.7483E-3 11 1 1 6292
    ribosome biogenesis 2.1778E-3 11 346 4 6292
    ribonucleoprotein complex biogenesis 2.9012E-3 11 374 4 6292
    ribosomal subunit assembly 3.9232E-3 11 55 2 6292
    ribosome assembly 5.2805E-3 11 64 2 6292
    ncRNA processing 5.2979E-3 11 215 3 6292
    organelle assembly 6.1157E-3 11 69 2 6292
    regulation of programmed cell death 6.9763E-3 11 4 1 6292
    regulation of apoptosis 6.9763E-3 11 4 1 6292
    regulation of cell death 6.9763E-3 11 4 1 6292
    ncRNA metabolic process 8.7081E-3 11 257 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 2.206E-10 11 212 8 6292
    structural molecule activity 9.3782E-9 11 339 8 6292
    nucleic acid binding 3.2527E-5 11 666 7 6292
    RNA binding 2.2654E-4 11 367 5 6292
    rRNA binding 3.2905E-4 11 16 2 6292
    binding 2.3113E-3 11 1294 7 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle