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Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components. Either of the two ribonucleoprotein complexes that associate to form a ribosome. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. A ribosome that is found in the cytosol of the cell. The cytosol is that part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. Examples of this component are found in Mus musculus, and in Bacterial and Archaeal species. The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. The large subunit of the ribosome that is found in the cytosol of the cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. Examples of this component are found in Mus musculus, and in Bacterial and Archaeal species. The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: cytosolic large ribosomal subunit
Acc: GO:0022625
Aspect: Cellular Component
Desc: The large subunit of the ribosome that is found in the cytosol of the cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. Examples of this component are found in Mus musculus, and in Bacterial and Archaeal species.
Synonyms:
  • GO:0009282
  • eukaryotic ribosomal LSU
  • 60S ribosomal subunit
  • 50S ribosomal subunit
  • GO:0030498
  • GO:0030872
  • GO:0005842
  • prokaryotic large ribosomal subunit
Proteins in PDR annotated with:
   This term: 354 [Search]
   Term or descendants: 354 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0022625 - cytosolic large ribosomal subunit (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle