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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 16 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
DIP2
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • ENP2
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • molecular_function
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • PWP2
  • cytoplasm
  • nuclear outer membrane
  • 90S preribosome
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • cytokinesis
  • ribosome biogenesis
  • snoRNA binding
  • ROK1
  • nuclear outer membrane
  • nucleolus
  • snoRNA localization
  • ribosome biogenesis
  • rRNA processing
  • ATPase activity
  • ATP-dependent RNA helicase activity
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP21
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • snoRNA binding
  • UTP30
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 3.3931E-21 16 72 12 6292
    nuclear outer membrane 9.9724E-16 16 86 10 6292
    nuclear membrane 3.5079E-15 16 97 10 6292
    outer membrane 1.7661E-12 16 178 10 6292
    organelle outer membrane 1.7661E-12 16 178 10 6292
    nuclear envelope 5.4353E-12 16 199 10 6292
    nucleolus 9.7865E-12 16 211 10 6292
    nuclear membrane-endoplasmic reticulum network 2.5302E-11 16 232 10 6292
    ribonucleoprotein complex 1.0506E-10 16 514 12 6292
    endomembrane system 5.2196E-9 16 398 10 6292
    nuclear lumen 1.8358E-8 16 453 10 6292
    nuclear part 4.6044E-8 16 1103 13 6292
    envelope 5.2395E-8 16 505 10 6292
    organelle envelope 5.2395E-8 16 505 10 6292
    organelle lumen 6.7223E-7 16 660 10 6292
    intracellular organelle lumen 6.7223E-7 16 660 10 6292
    membrane part 6.917E-7 16 662 10 6292
    organelle membrane 1.0501E-6 16 692 10 6292
    membrane-enclosed lumen 1.1699E-6 16 700 10 6292
    preribosome 1.2357E-6 16 34 4 6292
    non-membrane-bounded organelle 2.1518E-5 16 959 10 6292
    intracellular non-membrane-bounded organelle 2.1518E-5 16 959 10 6292
    macromolecular complex 5.6467E-5 16 1635 12 6292
    nucleus 8.2656E-5 16 2041 13 6292
    small-subunit processome 9.041E-5 16 6 2 6292
    membrane 1.5763E-4 16 1198 10 6292
    intracellular organelle part 3.0309E-4 16 2282 13 6292
    organelle part 3.0309E-4 16 2282 13 6292
    90S preribosome 8.0644E-4 16 17 2 6292
    Noc4p-Nop14p complex 5.0798E-3 16 2 1 6292
    nucleolar part 5.6318E-3 16 45 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 5.0115E-21 16 346 16 6292
    ribonucleoprotein complex biogenesis 1.7877E-20 16 374 16 6292
    cellular component biogenesis 4.1092E-16 16 694 16 6292
    rRNA processing 6.4177E-16 16 128 11 6292
    rRNA metabolic process 1.3869E-15 16 137 11 6292
    ncRNA processing 2.166E-13 16 215 11 6292
    maturation of SSU-rRNA 4.4404E-13 16 59 8 6292
    ncRNA metabolic process 1.5598E-12 16 257 11 6292
    RNA processing 1.1257E-10 16 380 11 6292
    RNA metabolic process 1.9341E-6 16 954 11 6292
    gene expression 3.8441E-5 16 1283 11 6292
    nucleic acid metabolic process 1.0065E-4 16 1415 11 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.6818E-4 16 1566 11 6292
    cellular nitrogen compound metabolic process 8.5298E-4 16 1770 11 6292
    nitrogen compound metabolic process 9.5191E-4 16 1791 11 6292
    ribosomal small subunit biogenesis 1.9016E-3 16 26 2 6292
    snoRNA localization 2.5429E-3 16 1 1 6292
    cellular process 3.565E-3 16 4426 16 6292
    ncRNA 5'-end processing 7.6106E-3 16 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.6106E-3 16 3 1 6292
    rRNA 5'-end processing 7.6106E-3 16 3 1 6292
    RNA 5'-end processing 7.6106E-3 16 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.6106E-3 16 3 1 6292
    cellular macromolecule metabolic process 8.4455E-3 16 2285 11 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 5.3268E-18 16 31 9 6292
    RNA binding 5.6369E-8 16 367 9 6292
    nucleic acid binding 9.1183E-6 16 666 9 6292
    binding 1.7921E-3 16 1294 9 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle