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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 14 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
DIP2
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • IMP4
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • rRNA primary transcript binding
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • RRP9
  • nuclear outer membrane
  • small nuclear ribonucleoprotein complex
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • snoRNA binding
  • SOF1
  • nuclear outer membrane
  • nucleolus
  • small nuclear ribonucleoprotein complex
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • snoRNA binding
  • UTP15
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 1.7341E-28 14 72 14 6292
    nuclear outer membrane 1.2744E-16 14 86 10 6292
    nuclear membrane 4.4974E-16 14 97 10 6292
    ribonucleoprotein complex 5.0021E-16 14 514 14 6292
    outer membrane 2.319E-13 14 178 10 6292
    organelle outer membrane 2.319E-13 14 178 10 6292
    nuclear envelope 7.1814E-13 14 199 10 6292
    nuclear membrane-endoplasmic reticulum network 3.376E-12 14 232 10 6292
    endomembrane system 7.3224E-10 14 398 10 6292
    macromolecular complex 6.1412E-9 14 1635 14 6292
    envelope 7.5963E-9 14 505 10 6292
    organelle envelope 7.5963E-9 14 505 10 6292
    membrane part 1.0534E-7 14 662 10 6292
    nucleolus 1.2142E-7 14 211 7 6292
    organelle membrane 1.6146E-7 14 692 10 6292
    small-subunit processome 1.7475E-7 14 6 3 6292
    preribosome 6.8484E-7 14 34 4 6292
    nuclear part 9.9756E-7 14 1103 11 6292
    nuclear lumen 2.1068E-5 14 453 7 6292
    membrane 2.8644E-5 14 1198 10 6292
    organelle lumen 2.399E-4 14 660 7 6292
    intracellular organelle lumen 2.399E-4 14 660 7 6292
    membrane-enclosed lumen 3.4772E-4 14 700 7 6292
    nucleus 5.2308E-4 14 2041 11 6292
    intracellular organelle part 1.5376E-3 14 2282 11 6292
    organelle part 1.5376E-3 14 2282 11 6292
    non-membrane-bounded organelle 2.3975E-3 14 959 7 6292
    intracellular non-membrane-bounded organelle 2.3975E-3 14 959 7 6292
    Noc4p-Nop14p complex 4.4455E-3 14 2 1 6292
    small nuclear ribonucleoprotein complex 8.3098E-3 14 63 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    maturation of SSU-rRNA 6.5642E-21 14 59 11 6292
    rRNA processing 2.6228E-19 14 128 12 6292
    rRNA metabolic process 6.1283E-19 14 137 12 6292
    ribosome biogenesis 1.7971E-18 14 346 14 6292
    ribonucleoprotein complex biogenesis 5.4511E-18 14 374 14 6292
    ncRNA processing 1.6044E-16 14 215 12 6292
    ncRNA metabolic process 1.4199E-15 14 257 12 6292
    cellular component biogenesis 3.5072E-14 14 694 14 6292
    RNA processing 1.6257E-13 14 380 12 6292
    rRNA modification 2.0584E-10 14 18 5 6292
    RNA metabolic process 9.4006E-9 14 954 12 6292
    RNA modification 2.732E-7 14 70 5 6292
    gene expression 2.985E-7 14 1283 12 6292
    nucleic acid metabolic process 9.2567E-7 14 1415 12 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.9666E-6 14 1566 12 6292
    cellular nitrogen compound metabolic process 1.1973E-5 14 1770 12 6292
    nitrogen compound metabolic process 1.3685E-5 14 1791 12 6292
    cellular macromolecule metabolic process 2.0876E-4 14 2285 12 6292
    macromolecule metabolic process 2.8291E-4 14 2349 12 6292
    ribosomal small subunit biogenesis 1.4494E-3 14 26 2 6292
    primary metabolic process 2.7048E-3 14 2896 12 6292
    cellular metabolic process 4.3936E-3 14 3033 12 6292
    macromolecule modification 5.9605E-3 14 569 5 6292
    metabolic process 6.6576E-3 14 3157 12 6292
    ncRNA 5'-end processing 6.6614E-3 14 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.6614E-3 14 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.6614E-3 14 3 1 6292
    rRNA 5'-end processing 6.6614E-3 14 3 1 6292
    RNA 5'-end processing 6.6614E-3 14 3 1 6292
    cellular process 7.2188E-3 14 4426 14 6292
    maturation of 5.8S rRNA 8.8726E-3 14 4 1 6292
    cleavage involved in rRNA processing 8.8726E-3 14 4 1 6292
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage involved in rRNA processing 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 3.8301E-16 14 31 8 6292
    RNA binding 1.0957E-8 14 367 9 6292
    nucleic acid binding 1.9424E-6 14 666 9 6292
    binding 4.6837E-4 14 1294 9 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle