From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.567626447603] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
RecQ helicase-Topo III complex | 1.5158E-7 | 2 | 3 | 2 | 6292 |
chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA recombination | 3.2544E-4 | 2 | 114 | 2 | 6292 |
DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
M phase of meiotic cell cycle | 6.427E-4 | 2 | 160 | 2 | 6292 |
meiosis | 6.427E-4 | 2 | 160 | 2 | 6292 |
meiotic cell cycle | 6.7534E-4 | 2 | 164 | 2 | 6292 |
anatomical structure homeostasis | 2.0592E-3 | 2 | 286 | 2 | 6292 |
telomere organization | 2.0592E-3 | 2 | 286 | 2 | 6292 |
telomere maintenance | 2.0592E-3 | 2 | 286 | 2 | 6292 |
M phase | 2.1762E-3 | 2 | 294 | 2 | 6292 |
cell cycle phase | 3.5621E-3 | 2 | 376 | 2 | 6292 |
telomere maintenance via telomere lengthening | 4.1283E-3 | 2 | 13 | 1 | 6292 |
telomere maintenance via telomerase | 4.1283E-3 | 2 | 13 | 1 | 6292 |
RNA-dependent DNA replication | 4.1283E-3 | 2 | 13 | 1 | 6292 |
homeostatic process | 4.1951E-3 | 2 | 408 | 2 | 6292 |
DNA unwinding involved in replication | 4.4455E-3 | 2 | 14 | 1 | 6292 |
regulation of DNA recombination | 4.7627E-3 | 2 | 15 | 1 | 6292 |
meiotic chromosome segregation | 5.0798E-3 | 2 | 16 | 1 | 6292 |
telomere maintenance via recombination | 5.0798E-3 | 2 | 16 | 1 | 6292 |
cell cycle process | 6.0534E-3 | 2 | 490 | 2 | 6292 |
DNA geometric change | 6.3477E-3 | 2 | 20 | 1 | 6292 |
DNA duplex unwinding | 6.3477E-3 | 2 | 20 | 1 | 6292 |
cell cycle | 6.95E-3 | 2 | 525 | 2 | 6292 |
regulation of biological quality | 7.6561E-3 | 2 | 551 | 2 | 6292 |
chromosome organization | 7.7677E-3 | 2 | 555 | 2 | 6292 |
DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
regulation of DNA metabolic process | 9.8303E-3 | 2 | 31 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA topoisomerase type I activity | 6.3568E-4 | 2 | 2 | 1 | 6292 |
DNA topoisomerase activity | 1.9064E-3 | 2 | 6 | 1 | 6292 |
ATP-dependent DNA helicase activity | 5.7138E-3 | 2 | 18 | 1 | 6292 |