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Protein Overview: CCZ1

General Information:
Name(s) found: CCZ1 / YBR131W [SGD]
Description(s) found:
Found 31 descriptions.
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  • Protein involved in vacuolar assembly, essential for autophagy and the cytoplasm-to-vacuole pathway [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 704 amino acids

    Gene Ontology:
    Cellular Component: membrane [TASLink to PubMed article]
    late endosome [TASLink to PubMed article]
    vacuole [IDALink to PubMed article]
    Biological Process: autophagy [IDALink to PubMed article]
    vesicle docking [IMPLink to PubMed article]
    vacuolar transport [IGILink to PubMed article][IMPLink to PubMed article]
    protein targeting to vacuole [IMPLink to PubMed article]
    autophagic vacuole fusion [IDALink to PubMed article]
    Molecular Function: guanyl-nucleotide exchange factor activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLHYITVFD PSRSTNENDT FKQLLLFHYF GTTDSIPSLN EKLSIIGVIQ GIWSLTSSCV  60
   61 NKDGEDLEKI IELNNDIIFC IKVESRFFIS LAISNISDDQ SAIPLQYLSA YLWLSYRFFK 120
  121 LLNGSFSGFN KDFRKLTDLL NEFVIPFWND IYLNLETVTN RSFTVMWPGF YKRANFQHSS 180
  181 YNPGEKNNVE ESWDAIILQN ILLDKKSYLG LKDILVYHLP KRTKAANRES MGTKTYGLVR 240
  241 NFTSDLNTLP DISNWLYHLH CTYGEISSHI LTGNVHFKEE LQVEEEQERS RDTNGRDEEE 300
  301 SQEQQRREHQ ETTQNNTSEL SLSERVIHNV TLPISFAYDA IHEVSTTTGV SGSLSMIMDY 360
  361 VPKPHWPFIS SSNKSADKNN YSNSNDNANS NAPLMAQSEA VGGTIGNSRF GFLISPLNSD 420
  421 LLPSSYQALK LNLNFENSKD KEDFYNCLFW YFDDFLIVIV CDPDFNKICE RDYLKDLSFQ 480
  481 LCQSMECLNN EILNSQNCDN VESFAYVIRD NVTKEIDSSV PFGSPKFTSD ESISTLQLAI 540
  541 NGIDQFINDN SNSLSLANWN PITIMGGSNA ISKKNTTEGF GNGVNDKTQK FKRKYLNFLN 600
  601 LMSAEKLWDL QVDVLQFLTS LQNSKRDPDY FQEERLLKLN NGVLCYIKEN NSNLIIIIKN 660
  661 WFQNNGTSKA AKQRNRFSSD SSKGSSLFQS LGRDVTDWWE SREI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CCZ1 MON1 YAP1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen NAS2 CCZ1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CCZ1 and SNF7 Huh WK, et al. (2003)
    View Data CCZ1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..704] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle