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Protein Overview: KISS1_RAT

General Information:
Name(s) found: KISS1_RAT [Swiss-Prot]
Description(s) found:
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  • gi|60389866|sp|Q7TSB7.1|KISS1_RAT RecName: Full=Metastasis-suppressor KiSS-1; AltName: Full=Kisspeptin-1; Contains: RecName: Full=Metastin; Contains: RecName: Full=Kisspeptin-10; AltName: Full=Metastin45-54; Flags: Precursor [NCBI NR]
  • gi|32140194|ref|NP_859043.1| KiSS-1 metastasis-suppressor [Rattus norvegicus] [NCBI NR]
  • gi|31744923|gb|AAP22375.1| metastin precursor [Rattus norvegicus] [NCBI NR]
  • gi|149058616|gb|EDM09773.1| KiSS-1 metastasis-suppressor [Rattus norvegicus] [NCBI NR]
  • Metastasis-suppressor KiSS-1 OS=Rattus norvegicus GN=Kiss1 PE=2 SV=1 [Swiss-Prot]
  • metastin; metastasis-suppressor [HMR_022704-rand.fasta]
  • KiSS-1 metastasis-suppressor [Rattus norvegicus]gi|31744923|gb|AAP22375.1| metastin precursor [Rattus norvegicus] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Metastasis-suppressor KiSS-1 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • KiSS-1 metastasis-suppressor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Metastasis-suppressor KiSS-1 precursor (Kisspeptin-1) [Contains: Metastin; Kisspeptin-10 (Metastin45-54)] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • metastin precursor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 METASTIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Kiss1 Metastasis-suppressor KiSS-1 [rat-ipi-250309-contam.fasta]
  • KiSS-1 metastasis-suppressor precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Metastasis-suppressor KiSS-1 OS=Rattus norvegicus GN=Kiss1 [011711_HMR.fasta]
  • Isoform of Q7TSB7, KiSS-1 metastasis-suppressor OS=Rattus norvegicus GN=Kiss1 PE=2 SV=1 [RAT.fasta.20160308]
    • Organism: Rattus norvegicus
    Length: 130 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IDA]
    cytoplasm [IDA]
    neuronal cell body [IDA]
    extracellular region [IEA]
    neuron projection [IDA]
    apical plasma membrane [IDA]
    Biological Process: generation of ovulation cycle rhythm [IMP]
    vesicle-mediated transport [IEA]
    positive regulation of growth hormone secretion [IDA]
    G-protein coupled receptor protein signaling pathway [UNKNOWN][TAS]
    negative regulation of cell proliferation [UNKNOWN][IDA]
    elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger [IDA]
    positive regulation of synaptic transmission [IDA]
    positive regulation of luteinizing hormone secretion [IDA][IMP]
    positive regulation of MAPKKK cascade [IMP]
    negative regulation of cell migration [UNKNOWN]
    [NOT]positive regulation of stress-activated MAPK cascade [IMP]
    elevation of cytosolic calcium ion concentration [IDA]
    Molecular Function: G-protein-coupled receptor binding [TAS]
    protein binding [UNKNOWN][IEA]
    kisspeptin receptor binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISLASWQLL LLLCVASFGE PLAKMAPVVN PEPTGQQSGP QELVNAWQKG PRYAESKPGA  60
   61 AGLRARRTSP CPPVENPTGH QRPPCATRSR LIPAPRGSVL VQREKDMSAY NWNSFGLRYG 120
  121 RRQVARAARG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle