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Protein Overview: gi|2555191, gi|2...

General Information:
Name(s) found: gi|29788774 [NCBI NR]
gi|2555191 [NCBI NR]
Description(s) found:
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  • gi|29788774|ref|NP_034519.2| histocompatibility 2, O region beta locus [Mus musculus] [NCBI NR]
  • gi|2555191|gb|AAB81530.1| IAbeta2 subunit [Mus musculus] [NCBI NR]
  • histocompatibility 2, O region beta locus [HMR_022704-rand.fasta]
  • histocompatibility 2, O region beta locus [Mus musculus]gi|2555191|gb|AAB81530.1| IAbeta2 subunit [Mus musculus] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 histocompatibility 2, O region beta locus [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • histocompatibility 2, O region beta locus [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • IAbeta2 subunit [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=H2-Ob histocompatibility 2, O region beta locus [mouse-ipi-250309-contam.fasta]
  • IPI:IPI00756478.1|TREMBL:O35424;Q31132;Q496U1;Q496U2|ENSEMBL:ENSMUSP00000092985|REFSEQ:NP_034519 Tax_Id=10090 Gene_Symbol=H2-Ob histocompatibility 2, O region beta locus [ipi.MOUSE.fasta.20090209]
  • IAbeta2 subunit OS=Mus musculus GN=H2-Ob [011711_HMR.fasta]
  • IAbeta2 subunit OS=Mus musculus GN=H2-Ob PE=2 SV=1 [uniprot-mouse-120502.fasta]
  • tr|O35424|O35424_MOUSE IAbeta2 subunit OS=Mus musculus GN=H2-Ob PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • IAbeta2 subunit OS=Mus musculus GN=H2-Ob PE=4 SV=1 [mouse-uniprot-290313-contam.fasta]
  • IAbeta2 subunit OS=Mus musculus GN=H2-Ob PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 271 amino acids

    Gene Ontology:
    Cellular Component: MHC class II protein complex [IEA]
    integral to membrane [IEA]
    intracellular [IDA]
    lysosome [UNKNOWN]
    Biological Process: antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [IEA]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGAGRAPWVV ALLVNLMRLD SFMIEGRDSP ENFVIQAKAD CYFTNGTEKV HLLVRFIFNL  60
   61 EEYLHFDSDL GMFVALTELG EPDADQWNKR LDLLETSRAA VNMVCRQKYK LGAPFTVERN 120
  121 VPPEVTVYPE RTPLLQQHNL LLCSVTGFYP GDISVKWFRN GQEERSGVMS TGLVRNGDWT 180
  181 FQTTVMLEMI PELGDIYSCL VEHPGLLRPV SVAWMAQSEY SWKKILSGAA VFLLGLIVFL 240
  241 VGVVIHLKAQ KASVETQPGN EASRESLHSQ P

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..271] PSI-BLAST 51.30103 Class II MHC beta chain, C-terminal domain; Class II MHC beta chain, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptide antigen binding
    		•  5.63215326620472 bayes_pls_golite062009
  • lipid antigen binding
    		•  4.82286265971588 bayes_pls_golite062009
  • olfactory receptor activity
    		•  4.58024710763591 bayes_pls_golite062009
  • endogenous lipid antigen binding
    		•  4.51527410976673 bayes_pls_golite062009
  • receptor activity
    		•  3.59560861549375 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  3.56598292218135 bayes_pls_golite062009
  • MHC class I receptor activity
    		•  3.46497995701625 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.44808015198907 bayes_pls_golite062009
  • signal transducer activity
    		•  3.44808015198907 bayes_pls_golite062009
  • antigen binding
    		•  2.27076537618453 bayes_pls_golite062009
  • binding
    		•  2.11682283742138 bayes_pls_golite062009
  • natural killer cell lectin-like receptor binding
    		•  2.02925074238378 bayes_pls_golite062009
  • protein binding
    		•  1.1543566056559 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  1.13521590137244 bayes_pls_golite062009
  • exogenous lipid antigen binding
    		•  0.763929387638141 bayes_pls_golite062009
  • IgG binding
    		•  0.66334714003323 bayes_pls_golite062009
  • peptide binding
    		•  0.59586638906248 bayes_pls_golite062009
  • receptor binding
    		•  0.46037337468987 bayes_pls_golite062009
  • MHC class II receptor activity
    		•  0.251167772391909 bayes_pls_golite062009
  • hydrolase activity
    		•  0.206657304371779 bayes_pls_golite062009
  • catalytic activity
    		•  0.115804452291889 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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