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Protein Overview: gi|45551030, gi|...

General Information:
Name(s) found: gi|45551031 [NCBI NR]
gi|45551030 [NCBI NR]
gi|45445665 [NCBI NR]
gi|45445664 [NCBI NR]
Description(s) found:
Found 10 descriptions.
SHOW ALL
  • gi|45551031|ref|NP_724566.2| aldehyde dehydrogenase type III, isoform G [Drosophila melanogaster] [NCBI NR]
  • gi|45551030|ref|NP_724565.2| aldehyde dehydrogenase type III, isoform F [Drosophila melanogaster] [NCBI NR]
  • gi|45445665|gb|AAM68900.2| aldehyde dehydrogenase type III, isoform G [Drosophila melanogaster] [NCBI NR]
  • gi|45445664|gb|AAM68899.2| aldehyde dehydrogenase type III, isoform F [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 626 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    Biological Process: cellular aldehyde metabolic process [IEA]
    oxidation reduction [IEA]
    Molecular Function: aldehyde dehydrogenase [NAD(P)+] activity [IEA]
    oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDNAIKPHP EANGAPINAG DRPITTVINI EPEPETESPI GIFTSQPESQ QQQPEQLQSE  60
   61 SESDRMANFD DTLQRARLAF SSGKTRNVSF RRKQLENLLR CYEEHENEII SALEADLRRP 120
  121 KQESLIVETE FMKNDIRHIL FQLDEWVQSE KPPKSFVNMM DDVQIYNDPF GVVLVIGAWN 180
  181 YPLQLLLVPV ASAIAAGNCV VIKPSEIAAN CAKFIADVIP KYLDNDCYPV VCGGPSETAE 240
  241 LLNQRFDYIF YTGSTRVGKI IHAAANKYLT PTTLELGGKS PCYIDKSVDM RTAVKRILWG 300
  301 KLINCGQTCI APDYILCSKE VQEKFIVEAK DVLKEWYGEN IQSSPDLSRV INANNFQRLL 360
  361 GLMKSGRVAV GGNYDASERF IEPTILVDVK ETDPIMEEEI FGPILPIFNV ESAYDAIKFI 420
  421 NARESPLVLY IFTPTAEVQN LFINGTQSGG LCVNDTIMHY AGKNPTSVNP KVAPIEMLMA 480
  481 VDYDNKEKPL VIYVFSNSNK LVKEFRRSTT SGGFSSNETI MHCGVDVLPF GGVGMSGMGR 540
  541 YHGKYGFETF THKKSCLGKD LSPLGEKLSS ARYPPYSDRK GSLLSFLLRK RRPLPNLHLS 600
  601 HVLAIGLGVG LTVLTNYYLQ GKLLSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..64] PSI-BLAST 163.0 Aldehyde reductase (dehydrogenase), ALDH
    2 View Details [65..626] PSI-BLAST 107.0 Aldehyde reductase (dehydrogenase), ALDH

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • oxidoreductase activity
    		•  4.47226217021998 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  4.34495776828926 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase [NAD(P)+] activity
    		•  3.64672165191647 bayes_pls_golite062009
  • 3-chloroallyl aldehyde dehydrogenase activity
    		•  3.37049090049734 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  3.2867555127991 bayes_pls_golite062009
  • aldehyde dehydrogenase (NAD) activity
    		•  2.81851373615334 bayes_pls_golite062009
  • catalytic activity
    		•  2.80804701752928 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase activity
    		•  2.71501590413507 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  2.6673036327943 bayes_pls_golite062009
  • methylmalonate-semialdehyde dehydrogenase (acylating) activity
    		•  1.59279206536309 bayes_pls_golite062009
  • binding
    		•  1.06673666884196 bayes_pls_golite062009
  • protein binding
    		•  0.894945263794726 bayes_pls_golite062009
  • glutamate-5-semialdehyde dehydrogenase activity
    		•  0.882678635212924 bayes_pls_golite062009
  • electron carrier activity
    		•  0.869224905025397 bayes_pls_golite062009
  • hydrolase activity
    		•  0.352374326884796 bayes_pls_golite062009
  • histidinol dehydrogenase activity
    		•  0.177840865580085 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle