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View Structure Prediction Details

Protein: gi|45551030, gi|...
Organism: Drosophila melanogaster
Length: 626 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|45551030, gi|....

Description E-value Query
Range
Subject
Range
AL1A1_SHEEP - Retinal dehydrogenase 1 OS=Ovis aries GN=ALDH1A1 PE=1 SV=2
570.0 [0..1] [500..1]

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Predicted Domain #1
Region A:
Residues: [1-64]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDNAIKPHP EANGAPINAG DRPITTVINI EPEPETESPI GIFTSQPESQ QQQPEQLQSE  60
   61 SESD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 163.0
Match: 1bxsA
Description: Aldehyde reductase (dehydrogenase), ALDH
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [65-626]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RMANFDDTLQ RARLAFSSGK TRNVSFRRKQ LENLLRCYEE HENEIISALE ADLRRPKQES  60
   61 LIVETEFMKN DIRHILFQLD EWVQSEKPPK SFVNMMDDVQ IYNDPFGVVL VIGAWNYPLQ 120
  121 LLLVPVASAI AAGNCVVIKP SEIAANCAKF IADVIPKYLD NDCYPVVCGG PSETAELLNQ 180
  181 RFDYIFYTGS TRVGKIIHAA ANKYLTPTTL ELGGKSPCYI DKSVDMRTAV KRILWGKLIN 240
  241 CGQTCIAPDY ILCSKEVQEK FIVEAKDVLK EWYGENIQSS PDLSRVINAN NFQRLLGLMK 300
  301 SGRVAVGGNY DASERFIEPT ILVDVKETDP IMEEEIFGPI LPIFNVESAY DAIKFINARE 360
  361 SPLVLYIFTP TAEVQNLFIN GTQSGGLCVN DTIMHYAGKN PTSVNPKVAP IEMLMAVDYD 420
  421 NKEKPLVIYV FSNSNKLVKE FRRSTTSGGF SSNETIMHCG VDVLPFGGVG MSGMGRYHGK 480
  481 YGFETFTHKK SCLGKDLSPL GEKLSSARYP PYSDRKGSLL SFLLRKRRPL PNLHLSHVLA 540
  541 IGLGVGLTVL TNYYLQGKLL SK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 107.0
Match: 1ad3A
Description: Aldehyde reductase (dehydrogenase), ALDH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 4.47226217021998 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 4.34495776828926 bayes_pls_golite062009
succinate-semialdehyde dehydrogenase [NAD(P)+] activity 3.64672165191647 bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity 3.37049090049734 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3.2867555127991 bayes_pls_golite062009
aldehyde dehydrogenase (NAD) activity 2.81851373615334 bayes_pls_golite062009
catalytic activity 2.80804701752928 bayes_pls_golite062009
succinate-semialdehyde dehydrogenase activity 2.71501590413507 bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity 2.6673036327943 bayes_pls_golite062009
methylmalonate-semialdehyde dehydrogenase (acylating) activity 1.59279206536309 bayes_pls_golite062009
binding 1.06673666884196 bayes_pls_golite062009
protein binding 0.894945263794726 bayes_pls_golite062009
glutamate-5-semialdehyde dehydrogenase activity 0.882678635212924 bayes_pls_golite062009
electron carrier activity 0.869224905025397 bayes_pls_golite062009
hydrolase activity 0.352374326884796 bayes_pls_golite062009
histidinol dehydrogenase activity 0.177840865580085 bayes_pls_golite062009

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