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Protein Overview: ETHR-PB

General Information:
Name(s) found: ETHR-PB / FBpp0083455 [FlyBase]
Description(s) found:
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  • gi|45553451|ref|NP_996255.1| ETHR, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|45446579|gb|AAS65191.1| ETHR, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|29500945|gb|AAO74887.1| putative ETH receptor splicing variant b [Drosophila melanogaster] [NCBI NR]
  • The gene ETHR is referred to in FlyBase by the symbol Dmel\ETHR (CG5911, FBgn0038874). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17073026..17090856. It has the cytological map location 93D1-93D2. There is experimental evidence that it has the molecular function</span>: ecdysis-triggering hormone receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: G-protein coupled receptor protein signaling pathway. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • (AAS65191) CG5911-PB [DrosMelano7227.FASTAC.txt]
  • CG5911-PB, isoform B [Drosophila melanogaster]gi|29500945|gb|AAO74887.1| putative ETH receptor splicing variant b [Drosophila melanogaster]gi|45553451|ref|NP_996255.1| CG5911-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:join(17084656..17084745,17085193..17085355,17085429..17085609,17089742..17090693); ID=FBpp0083455; name=ETHR-PB; parent=FBgn0038874,FBtr0084053; dbxref=FlyBase:FBpp0083455,FlyBase_Annotation_IDs:CG5911-PB,GB_protein:AAS65191.1,REFSEQ: [fly-100309-contam.fasta]
  • CG5911-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • ETHR CG5911-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • putative ETH receptor splicing variant b [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:join(17084656..17084745,17085193..17085355,17085429..17085609,17089742..17090693); ID=FBpp0083455; name=ETHR-PB; parent=FBgn0038874,FBtr0084053; dbxref=FlyBase:FBpp0083455,FlyBase_Annotation_IDs:CG5911-PB,GB_protein:AAS65191.1,REFSEQ:NP_996255,GB_protein:AAS65191; MD5=cfef199881b057c41497d1047fb9cdea; length=461; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(17084656..17084745,17085193..17085355,17085429..17085609,17089742..17090693); ID=FBpp0083455; name=ETHR-PB; parent=FBgn0038874,FBtr0084053; dbxref=FlyBase:FBpp0083455,FlyBase_Annotation_IDs:CG5911-PB,GB_protein:AAS65191.1,REFSEQ:NP_996255,GB_protein:AAS65191; MD5=cfef199881b057c41497d1047fb9cdea; length=461; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • ETHR, isoform B OS=Drosophila melanogaster GN=ETHR PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:join(17084656..17084745,17085193..17085355,17085429..17085609,17089742..17090693); ID=FBpp0083455; name=ETHR-PB; parent=FBgn0038874,FBtr0084053; dbxref=FlyBase:FBpp0083455,FlyBase_Annotation_IDs:CG5911-PB,GB_protein:AAS65191.1,REFSEQ:NP_996255,GB_protein:AAS65191,FlyMine:FBpp0083455,modMine:FBpp0083455; MD5=cfef199881b057c41497d1047fb9cdea; length=461; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:join(21258934..21259023,21259471..21259633,21259707..21259887,21264020..21264971); ID=FBpp0083455; name=ETHR-PB; parent=FBgn0038874,FBtr0084053; dbxref=FlyBase:FBpp0083455,FlyBase_Annotation_IDs:CG5911-PB,GB_protein:AAS65191.1,REFSEQ:NP_996255,GB_protein:AAS65191,FlyMine:FBpp0083455,modMine:FBpp0083455; MD5=cfef199881b057c41497d1047fb9cdea; length=461; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(21258934..21259023,21259471..21259633,21259707..21259887,21264020..21264971); ID=FBpp0083455; name=ETHR-PB; parent=FBgn0038874,FBtr0084053; dbxref=FlyBase:FBpp0083455,FlyBase_Annotation_IDs:CG5911-PB,GB_protein:AAS65191.1,REFSEQ:NP_996255,GB_protein:AAS65191,FlyMine:FBpp0083455,modMine:FBpp0083455; MD5=cfef199881b057c41497d1047fb9cdea; length=461; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9VDC4, ETHR, isoform B OS=Drosophila melanogaster GN=ETHR PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0083455 type=protein; loc=3R:join(21258934..21259023,21259471..21259633,21259707..21259887,21264020..21264971); ID=FBpp0083455; name=ETHR-PB; parent=FBgn0038874,FBtr0084053; dbxref=FlyBase:FBpp0083455,FlyBase_Annotation_IDs:CG5911-PB,GB_protein:AAS65191.1,REFSEQ:NP_996255,GB_protein:AAS65191,FlyMine:FBpp0083455,modMine:FBpp0083455; MD5=cfef199881b057c41497d1047fb9cdea; length=461; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:join(21258934..21259023,21259471..21259633,21259707..21259887,21264020..21264971); ID=FBpp0083455; name=ETHR-PB; parent=FBgn0038874,FBtr0084053; dbxref=FlyBase:FBpp0083455,FlyBase_Annotation_IDs:CG5911-PB,GB_protein:AAS65191.1,REFSEQ:NP_996255,GB_protein:AAS65191,UniProt/TrEMBL:Q86C62,FlyMine:FBpp0083455,modMine:FBpp0083455; MD5=cfef199881b057c41497d1047fb9cdea; length=461; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 461 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISS]
    Biological Process: G-protein coupled receptor protein signaling pathway [ISS][NAS]
    Molecular Function: peptide receptor activity, G-protein coupled [ISS][NAS]
    neuropeptide receptor activity [ISS]
    ecdysis-triggering hormone receptor activity [IDA][NAS]
    G-protein coupled amine receptor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPQIPSYIR TTAMFFCIVI MLLGVVGNVM VPIVIVKTKD MRNSTNIFLT NLSIADLLVL  60
   61 LVCTPTVLVE VNTRPETWVL GHEMCKAVPF VELTVAHASV LTILAISFER YYAICEPLKA 120
  121 GYVCTKGRAI LICVLAWGIA ALFTSPIIAI STYSVEPYGD GTDAPVCTTA ADGFWSIFYF 180
  181 VGCITVFFFL PFGILVLLYA AIAYKLLRPN NAFHRPTSPQ PQQPSGGATS GSSQVPSTKG 240
  241 NSHQQSNGMR KHRKQVIFML VAVVSSFFVC LLPFRAFTLW VILASAEDVE GLGIAGYYNL 300
  301 LYFSRFMLYL NSAMNPILYN LMSSKFRSGF WRLLLTCLGQ RPHHHHRHHY HQRQHPTAGG 360
  361 SGRNASTRQE QDAEEGAALA GTTSARHPRR TLRREATFLI NSISTSSGTD RTTSSSAWRS 420
  421 NSLSISGLSE RERGILGAAI IGTTAATVTT ACLQERRASK I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..355] PSI-BLAST 45.154902 Rhodopsin
    2 View Details [356..461] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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