Protein Overview: Pvr-PE

General Information:
Name(s) found:	Pvr-PE / FBpp0089342 [FlyBase]
Description(s) found: Found 18 descriptions. SHOW ALL	The gene PDGF- and VEGF-receptor related is referred to in FlyBase by the symbol Dmel\Pvr (CG8222, FBgn0032006). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:8220980..8239875. It has the cytological map location 28F4-28F5. There is experimental evidence that it has the molecular function</span>: transmembrane receptor protein tyrosine kinase activity; protein binding. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; regulation of developmental process; actin filament-based process; organelle organization; cellular component movement; response to DNA damage stimulus; immune response; cell projection organization; gland morphogenesis; reproductive process in a multicellular organism; cell cycle. 61 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; hemocyte; embryonic/larval hemocoel; embryonic nervous system; nervous system; female germline cyst; adult segment; adult mesothoracic segment; thoracic segment; embryonic glial cell; Kc167 cell-line; dorsal thoracic disc; multi-cell-component structure; peripheral nervous system. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1503 amino acids
Gene Ontology:
Cellular Component:	plasma membrane [IDA][ISS][NAS]
Biological Process:	hemocyte migration [IMP][TAS] regulation of cell shape [IMP] hemocyte proliferation [TAS] hemopoiesis [IEP] cell projection assembly [IMP] regulation of hemocyte differentiation [IMP] hemocyte differentiation [NAS] actin filament organization [IMP] border follicle cell migration [IGI][IMP][TAS] protein amino acid phosphorylation [IEA][NAS] response to DNA damage stimulus [IMP] salivary gland morphogenesis [IMP] ventral cord development [IMP] mitotic spindle elongation [IMP] vascular endothelial growth factor receptor signaling pathway [ISS] antimicrobial humoral response [IMP] actin cytoskeleton organization [IMP]
Molecular Function:	ATP binding [IEA] protein tyrosine kinase activity [NAS] protein binding [IPI] transmembrane receptor protein tyrosine kinase activity [IPI][ISS] vascular endothelial growth factor receptor activity [ISS][NAS] platelet-derived growth factor receptor activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMLPRLILL PLLLILRISW SDAVPLQQFS PDPDDSIENC GGENGAPLMT PCKSAIILDA  60
   61 QTSTTLKCED DEPMSWWTSQ SQYVHVKSFD NTEDPARPFG TSLHLIEVTA DYVAAYYCVK 120
  121 TSKFSQIAKE EQSDEAMIEL VNQGYASSIY VYVNDPDTKL VDSHNVVTAR QYTDVVIPCK 180
  181 PAMPDTEVLL ETSNGEMHSS KSVGRYDPQR GFTIEIRSIV DGGDYYCRPN PPFPHNEEEM 240
  241 TSIEVRFIED GKPLPKPVIR SSVEHHVFTD TNFTLDCEQS AYVESVYGME WFTPSRDENR 300
  301 IFASQSRTDP KTRNSTHQTG RSTLTVLNAQ PSDTGLYKCV TTDNSNQNVQ RATYRIKVLK 360
  361 QNESYLNVGE PSGHYNVQEY ANRTIQMTAN FEGFPTPSFS WFKPDGTEVR QSENNFKILS 420
  421 TELSTMLQVL NAQLQDSGTY VLRGSNSFGV VQREYNVSVM DAPALKMSDA YVQVGSVARL 480
  481 ECTVRSYPPA IVTFFFRPCS LEPQWPTCSV LNQNFSLPSE QEKYQFQTRP RPGKLSVERI 540
  541 YEVSFLPTEP GILTCIAQNI IDGKERRTLT KAHVLLGNIS ENMTIYGFDK DHKIAKEDNV 600
  601 NFTCEALAYH FDGNLKWFIN GEDLKESDSV HIETSHTKYS YKSTVHITTI SDRDRGTYEC 660
  661 RAYHNDKDAV YSSREIDLYV HDPSAPQWTN GGQEGHSKIK RKLSQTLELE CASTAVPVAI 720
  721 VRWFKDDKEV TESKLRHIIE KESKLLITHL YPGDEGVYKC VVENRLDRIE RSFTVVISDL 780
  781 PGISMAWVWF GVILFLILIG LCVFLAVRYQ KEHKRHLALK AAGLANFEEG AVGHINPDLT 840
  841 LDEQAELLPY NREFEFPREN LKLGKQLGAG AFGVVLKGEA KGIRREEPTT TVAVKMVKAT 900
  901 ADNEVVRALV SELKIMVHLG QHLNVVNLLG AVTKNIAKRE LMVIVEYCRF GNIQNFLLRN 960
  961 RKCFINQINP DTDHIDPSIM TQRMSDNYEL HRDTNGGGLK YANVGFPIHS YINEPHNNNT1020
 1021 QPPTHRRNSD NDPRSGTRAG RTGSGTATYS YDRQMDTCAT VMTTVPEDDQ IMSNNSVQPA1080
 1081 WRSNYKTDST EAMTVTTVDL ISWAFQVARG MDYLSSKKVL HGDLAARNIL LCEDNVVKIC1140
 1141 DFGLARSMYR GDNYKKSENG KLPIKWLALE SLSDHVFSTY SDVWSYGIVL WEMFSLAKVP1200
 1201 YPGIDPNQEL FNKLNDGYRM EKPKFANQEL YEIMLECWRK NPESRPLFAE LEKRFANMLG1260
 1261 EDVASHYLDL NNPYMQSNIE YMKKQSTDYL ALMGSPDELA PAAPRYVNGH IVPDIRIEEL1320
 1321 PDDYMEMSRD SDPDACTAIF SPTRLEGESS DFPDFSSETT FNFPGARQSP TLSNNLNSGS1380
 1381 SKPLRKKNGM PTVDVADQAP EEIPMLHRSS TGSDGSPEQG RRFNQALKQQ YVTPTPSPRH1440
 1441 HVETKLNGEP SENYVNMKPP RKNIPGKTTT GGGGAAAGAS TEAFSNPSYQ PLSTVNEKEQ1500
 1501 RRY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Pvr-PE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: