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Protein Overview: AP-1gamma-PC, FB...

General Information:
Name(s) found: FBpp0301194 [FlyBase]
AP-1gamma-PC / FBpp0071233 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=X:join(9005022..9005038,9005115..9005176,9005420..9005561,9005631..9005819,9005887..9006125,9006196..9006272,9006783..9006800,9007676..9007932,9008008..9008603,9008667..9008805,9008871..9009159,9009229..9009744,9009798..9009941,9010004..9010111,9010179..9010295); ID=FBpp0301194; name=AP-1gamma-PH; parent=FBgn0030089,FBtr0309255; dbxref=FlyBase:FBpp0301194,FlyBase_Annotation_IDs:CG9113-PH,REFSEQ:NP_001245590,GB_protein:AFH07304; MD5=e4511617cef800a41a771b2d7aa18c63; length=969; release=r5.56; species=Dmel; [FlyBase]
  • The gene AP-1Ã?&#142;Ã?³ is referred to in FlyBase by the symbol Dmel\AP-1Ã?&#142;Ã?³ (CG9113, FBgn0030089). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9002726..9011773. It has the cytological map location 8C9-8C10. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; protein transporter activity. It is reported to be involved in the biological process</span>: vesicle coating; neurotransmitter secretion; synaptic vesicle coating. 3 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 969 amino acids

    Gene Ontology:
    Cellular Component: synaptic vesicle [TAS]
    clathrin adaptor complex [IEA]
    Golgi apparatus part [IEA]
    coated vesicle [TAS]
    Biological Process: vesicle coating [TAS]
    vesicle-mediated transport [IEA]
    synaptic vesicle coating [TAS]
    intracellular protein transport [IEA]
    neurotransmitter secretion [NAS]
    Molecular Function: protein binding [IEA]
    protein transporter activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSEHGFNPA FNMATIRQAF TEAVERVRMP TPTRLRDLIR QIRAARTAAE ERAVVNKECA  60
   61 YIRSTFREED SVWRCRNIAK LLYIHMLGYP AHFGQLECLK LTASTRFTDK RIGYLGAMLL 120
  121 LDERQDVHLL ITNCLKNDLN SSTQFVVGLA LCTLGAIASP EMARDLASEV ERLMKSPNTY 180
  181 IRKKATLCAF RVIRRVPELM EIFLPATRSL LSEKNHGILI TGVTLITEMC ENSSDTLMHF 240
  241 KKDSGNREIV PNLVRILKNL ILGGYSPEHD VSGVSDPFLQ VKILRLLRIL GHNDPDASEA 300
  301 MNDILAQVAT NTETSKNVGN TILYETVLSI MDIRSEGGLR VLAVNILGRF LLNSDKNIRY 360
  361 VALNTLLRTV HADTSAVQRH RTTILECLKD PDVSIRRRAM ELSFALINAQ NIRTMTKELL 420
  421 LFLEKADAEF KAQCSSGMIL AAERYSPTTR WHLDTQLSVL IAAGNYVRDD VVSSTIQLVS 480
  481 SSPVPEQTYI TNRFWESLQV ANHCEDKQPL LQVAVWAIGE YGDLFMYGAN EDEFERPTES 540
  541 DLIAVYYKFL TSAQVSTTSK QYALVSLAKL STRLQQCVEE IQALITSFGS HLNVDLQQRG 600
  601 VEFTQLFGHY KHLRPPLLEK MPAMQISRIS SQNGESGGGS FDDNSPDVIE NGVEGGGGGG 660
  661 HSLIESNMNT LGDNTNILLD LLGSTDLSAG GAGDLVAATD LSNAVHKKNS RNANDVVAPV 720
  721 SNNQDLLDLL DLDLSAPSST TTGAPAGGGG GGGIVALVGD NNQSSAANMN NMLGGLDLGG 780
  781 FGSGLDSSAS IPTNGNDLAS MLGGLGAPPA ASPSLAASAP VGNLIDGHAG SLLADLNPTA 840
  841 ASNNVVVPPQ GPRLTALDKD GLLVQLVSVR GSDCMRIYMT TTNNSDNTLD QYLLQAAVQR 900
  901 SFQLQMLTPS GSVLPPGGVI TQEMRVVATS NATLRMRLRI QYVLDGQQQV EQTEVSGFPE 960
  961 QQPAPAAAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..689] PSI-BLAST 146.0 AP1 clathrin adaptor core
    2 View Details [690..759] deduced N/A No confident structure predictions are available.
    3 View Details [760..969] PSI-BLAST 18.69897 Gamma1-adaptin domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.73706375360191 bayes_pls_golite062009
  • protein binding
    		•  1.07977592306595 bayes_pls_golite062009
  • transporter activity
    		•  0.169557557237959 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle