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Protein Overview: fd3F-PB

General Information:
Name(s) found: fd3F-PB / FBpp0070577 [FlyBase]
Description(s) found:
Found 15 descriptions.
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  • The gene forkhead domain 3F is referred to in FlyBase by the symbol Dmel\fd3F (CG12632, FBgn0061173). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3696349..3704546. It has the cytological map location 3F2. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 360 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: regulation of transcription, DNA-dependent [IEA]
    dendrite morphogenesis [IMP]
    Molecular Function: transcription factor activity [ISS]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWLKSKTNHR KTSRPKKPPF TYTELIEYAL EDKGELTVSG IYQWISDRFP YYKSNDDRWK  60
   61 NSVRHNLSIN PHFRKGVKAP QGAGHLWAIS SGDSAENVLA WEHKKQRLDL FFKMESINRE 120
  121 RIQQHQQQQQ LQQHQQQHQQ HSPQQKQHSA AQQQHMPQAS SCMYDEAAVA VATLTQEMMQ 180
  181 TNSGGGSTET SQQQQQQQQH HHHHSHQNHQ NHNQHHQRLL PFNDLLSDDE LRKTAGQILN 240
  241 GIHREVEVQS VNSIISTYHD VLLDNDYLNP IHKDVVVTES VLRQQHGTNL GGGNNNQNNQ 300
  301 MGGNSHMGGG NSQYYITEID PMELGIQMSH QVEPSEEEVL FSDEFNLNYF GYNPGSDIVA 360
  361

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] PSI-BLAST 33.154902 Adipocyte-transcription factor FREAC-11 (s12, fkh-14)
    2 View Details [106..214] deduced N/A No confident structure predictions are available.
    3 View Details [215..360] MSA 9.321997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.55329976718261 bayes_pls_golite062009
  • DNA binding
    		•  5.08959163553491 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.99681957904233 bayes_pls_golite062009
  • transcription factor activity
    		•  4.33152142980289 bayes_pls_golite062009
  • transcription activator activity
    		•  3.70589483230587 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.58179858678904 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.60738445921725 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.22485867684613 bayes_pls_golite062009
  • protein binding
    		•  1.80415286835431 bayes_pls_golite062009
  • transcription factor binding
    		•  0.85714789329232 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.66743181561551 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.23177057841536 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle