Protein Overview: dnc-PG

General Information:
Name(s) found:	dnc-PG / FBpp0070496 [FlyBase]
Description(s) found: Found 18 descriptions. SHOW ALL	The gene dunce is referred to in FlyBase by the symbol Dmel\dnc (CG32498, FBgn0000479). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3070475..3233360. It has the cytological map location 3C9-3D1. Based on sequence similarity, it is predicted to have molecular function</span>: 3',5'-cyclic-AMP phosphodiesterase activity. There is experimental evidence that it is involved in the biological process</span>: synaptic transmission; conditioned taste aversion; short-term memory; axon extension. 72 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: anatomical structure; organ system; embryonic neuron; embryonic nervous system; female germline cyst; nervous system; developing anatomical structure; egg; multi-cell-component structure; synapse; postsynaptic membrane; adult brain; neuromuscular junction. It has 12 annotated transcripts and 12 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	814 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATEAEGEEF DVDPMDEDDE DQTYDRETEE FYSNIQDAAG TGSSSRSKRS SLFSRSDSSA  60
   61 TTTSSSGGGT FTGGKRRSAA SILSSSMCSD LMTSDRRSST ATEYSVKSVT TGNTSQRRSS 120
  121 GRIRRYVSRM TIAGARRRTT GSFDVENGQG ARSPLEGGSP SAGLVLQNLP QRRESFLYRS 180
  181 DSDFEMSPKS MSRNSSIASE SHGEDLIVTP FAQILASLRS VRNNLLSLTN VPASNKSRRP 240
  241 NQSSSASRSG NPPGAPLSQG EEAYTRLATD TIEELDWCLD QLETIQTHRS VSDMASLKFK 300
  301 RMLNKELSHF SESSRSGNQI SEYICSTFLD KQQEFDLPSL RVEDNPELVA ANAAAGQQSA 360
  361 GQYARSRSPR GPPMSQISGV KRPLSHTNSF TGERLPTFGV ETPRENELGT LLGELDTWGI 420
  421 QIFSIGEFSV NRPLTCVAYT IFQSRELLTS LMIPPKTFLN FMSTLEDHYV KDNPFHNSLH 480
  481 AADVTQSTNV LLNTPALEGV FTPLEVGGAL FAACIHDVDH PGLTNQFLVN SSSELALMYN 540
  541 DESVLENHHL AVAFKLLQNQ GCDIFCNMQK KQRQTLRKMV IDIVLSTDMS KHMSLLADLK 600
  601 TMVETKKVAG SGVLLLDNYT DRIQVLENLV HCADLSNPTK PLPLYKRWVA LLMEEFFLQG 660
  661 DKERESGMDI SPMCDRHNAT IEKSQVGFID YIVHPLWETW ADLVHPDAQD ILDTLEENRD 720
  721 YYQSMIPPSP PPSGVDENPQ EDRIRFQVTL EESDQENLAE LEEGDESGGE STTTGTTGTT 780
  781 AASALSGAGG GGGGGGGMAP RTGGCQNQPQ HGGM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
cyclic-nucleotide phosphodiesterase activity	3.86434485322172	bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity	3.8566356686502	bayes_pls_golite062009
phosphoric diester hydrolase activity	3.16734214417311	bayes_pls_golite062009
3',5'-cyclic-AMP phosphodiesterase activity	2.29938697204184	bayes_pls_golite062009
3',5'-cyclic-GMP phosphodiesterase activity	2.29281173183086	bayes_pls_golite062009
catalytic activity	1.44092158711463	bayes_pls_golite062009
hydrolase activity	1.06080266556153	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.815214868148798	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.196287846714023	bayes_pls_golite062009
binding	0.0840884387362641	bayes_pls_golite062009

Term	Confidence	Notes
cyclic-nucleotide phosphodiesterase activity	3.86434485322172	bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity	3.8566356686502	bayes_pls_golite062009
phosphoric diester hydrolase activity	3.16734214417311	bayes_pls_golite062009
3',5'-cyclic-AMP phosphodiesterase activity	2.29938697204184	bayes_pls_golite062009
3',5'-cyclic-GMP phosphodiesterase activity	2.29281173183086	bayes_pls_golite062009
catalytic activity	1.44092158711463	bayes_pls_golite062009
hydrolase activity	1.06080266556153	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.815214868148798	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.196287846714023	bayes_pls_golite062009
binding	0.0840884387362641	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.93

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..97]	MSA	1.082983	View MSA. No confident structure predictions are available.
2	View Details	[98..265]	MSA	6.145997	View MSA. No confident structure predictions are available.
3	View Details	[266..383]	MSA	1.200989	View MSA. No confident structure predictions are available.
4	View Details	[384..814]	PSI-BLAST	136.0	No description for 2fm0A was found.

Protein Overview: dnc-PG

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: