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View Structure Prediction Details

Protein: dnc-PG
Organism: Drosophila melanogaster
Length: 814 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dnc-PG.

Description E-value Query
Range
Subject
Range
dnc-PN - The gene dunce is referred to in FlyBase by the symbol Dmel\dnc (CG32498, FBgn0000479). It is a prot...
806.0 [0..1] [814..170]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATEAEGEEF DVDPMDEDDE DQTYDRETEE FYSNIQDAAG TGSSSRSKRS SLFSRSDSSA  60
   61 TTTSSSGGGT FTGGKRRSAA SILSSSMCSD LMTSDRR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [98-265]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSTATEYSVK SVTTGNTSQR RSSGRIRRYV SRMTIAGARR RTTGSFDVEN GQGARSPLEG  60
   61 GSPSAGLVLQ NLPQRRESFL YRSDSDFEMS PKSMSRNSSI ASESHGEDLI VTPFAQILAS 120
  121 LRSVRNNLLS LTNVPASNKS RRPNQSSSAS RSGNPPGAPL SQGEEAYT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [266-383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLATDTIEEL DWCLDQLETI QTHRSVSDMA SLKFKRMLNK ELSHFSESSR SGNQISEYIC  60
   61 STFLDKQQEF DLPSLRVEDN PELVAANAAA GQQSAGQYAR SRSPRGPPMS QISGVKRP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
cyclic-nucleotide phosphodiesterase activity 3.86434485322172 bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity 3.8566356686502 bayes_pls_golite062009
phosphoric diester hydrolase activity 3.16734214417311 bayes_pls_golite062009
3',5'-cyclic-AMP phosphodiesterase activity 2.29938697204184 bayes_pls_golite062009
3',5'-cyclic-GMP phosphodiesterase activity 2.29281173183086 bayes_pls_golite062009
catalytic activity 1.44092158711463 bayes_pls_golite062009
hydrolase activity 1.06080266556153 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.815214868148798 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.196287846714023 bayes_pls_golite062009
binding 0.0840884387362641 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [384-814]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSHTNSFTGE RLPTFGVETP RENELGTLLG ELDTWGIQIF SIGEFSVNRP LTCVAYTIFQ  60
   61 SRELLTSLMI PPKTFLNFMS TLEDHYVKDN PFHNSLHAAD VTQSTNVLLN TPALEGVFTP 120
  121 LEVGGALFAA CIHDVDHPGL TNQFLVNSSS ELALMYNDES VLENHHLAVA FKLLQNQGCD 180
  181 IFCNMQKKQR QTLRKMVIDI VLSTDMSKHM SLLADLKTMV ETKKVAGSGV LLLDNYTDRI 240
  241 QVLENLVHCA DLSNPTKPLP LYKRWVALLM EEFFLQGDKE RESGMDISPM CDRHNATIEK 300
  301 SQVGFIDYIV HPLWETWADL VHPDAQDILD TLEENRDYYQ SMIPPSPPPS GVDENPQEDR 360
  361 IRFQVTLEES DQENLAELEE GDESGGESTT TGTTGTTAAS ALSGAGGGGG GGGGMAPRTG 420
  421 GCQNQPQHGG M

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 136.0
Match: 2fm0A
Description: No description for 2fm0A was found.

Predicted functions:

Term Confidence Notes
cyclic-nucleotide phosphodiesterase activity 3.86434485322172 bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity 3.8566356686502 bayes_pls_golite062009
phosphoric diester hydrolase activity 3.16734214417311 bayes_pls_golite062009
3',5'-cyclic-AMP phosphodiesterase activity 2.29938697204184 bayes_pls_golite062009
3',5'-cyclic-GMP phosphodiesterase activity 2.29281173183086 bayes_pls_golite062009
catalytic activity 1.44092158711463 bayes_pls_golite062009
hydrolase activity 1.06080266556153 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.815214868148798 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.196287846714023 bayes_pls_golite062009
binding 0.0840884387362641 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle