Protein Overview: gi|7511903, gi|4...

General Information:
Name(s) found:	gi\|7511903 [NCBI NR] gi\|45551208 [NCBI NR] gi\|45446783 [NCBI NR] gi\|4165455 [NCBI NR]
Description(s) found: SHOW ONLY BEST	pir\|\|T13744 hypothetical protein 22E5.5 - fruit fly (Drosophila melanogaster) [NCBI NR] gi\|45551208\|ref\|NP_726789.2\| CG4199, isoform F [Drosophila melanogaster] [NCBI NR] gi\|45446783\|gb\|AAN09070.2\| CG4199, isoform F [Drosophila melanogaster] [NCBI NR] gi\|4165455\|emb\|CAA21128.1\| EG:22E5.5 [Drosophila melanogaster] [NCBI NR] (O77266) EG:22E5.5 protein [DrosMelano7227.FASTAC.txt] (AAN09070) CG4199-PF [DrosMelano7227.FASTAC.txt] CG4199-PF, isoform F [Drosophila melanogaster]gi\|45551208\|ref\|NP_726789.2\| CG4199-PF [Drosophila melanogaster]gi\|7511903\|pir\|\|T13744 hypothetical protein 22E5.5 - fruit fly (Drosophila melanogaster)gi\|4165455\|emb\|CAA21128.1\| EG:22E5.5 [Drosophila melan [nrdb_11152004_Chlamydomonas] CG4199-PF, isoform F [Drosophila melanogaster] [nr-271106-contam.fasta] EG:22E5.5 [Drosophila melanogaster] [nr-271106-contam.fasta] EG:22E5.5 protein OS=Drosophila melanogaster GN=EG:22E5.5 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
Organism:	Drosophila melanogaster
Length:	665 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA]
Biological Process:	cell redox homeostasis [IEA] oxidation reduction [IEA]
Molecular Function:	FAD binding [IEA] oxidoreductase activity [IEA] 2 iron, 2 sulfur cluster binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDWPFCLSV SKVGGLQIRK KWQSPRTALS LVKTKRAFEG LLRIRKLPSS QSWRILNAPS  60
   61 FASHINNRLL NTMGSVNCKE YKTTGSTPKK EKSTGGAVGS YQSKCSNQSP STTMSTEESS 120
  121 PDSEYTSAVP VDCRVTDLKE NEMKQVDFDE DTRVLLVKQN DRLLAVGAKC THYGAPLQTG 180
  181 ALGLGRVRCP WHGACFNLEN GDIEDFPGLD SLPCYRVEVG NEGQVMLRAK RSDLVNNKRL 240
  241 KNMVRRKPDD QRVFIVVGGG PSGAVAVETI RQEGFTGRLI FVCREDYLPY DRVKISKAMN 300
  301 LEIEQLRFRD EEFYKEYDIE LWQGVAAEKL DTAQKELHCS NGYVVKYDKI YLATGCSAFR 360
  361 PPIPGVNLEN VRTVRELADT KAILASITPE SRVVCLGSSF IALEAAAGLV SKVQSVTVVG 420
  421 RENVPLKAAF GAEIGQRVLQ LFEDNKVVMR MESGIAEIVG NEDGKVSEVV LVDDTRLPCD 480
  481 LLILGTGSKL NTQFLAKSGV KVNRNGSVDV TDFLESNVPD VYVGGDIANA HIHGLAHDRV 540
  541 NIGHYQLAQY HGRVAAINMC GGVKKLEAVP FFFTLIFGKG IRYAGHGSYK DVIIDGSMED 600
  601 FKFVAYFINE ADTVTAVASC GRDPIVAQFA ELISQGKCLG RGQIEDPATR EDWTKKLGQP 660
  661 LPQVR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..124]	FFAS03	0.965	Interleukin-4 receptor alpha chain
2	View Details	[125..577]	PSI-BLAST	15.69897	Dihydropyrimidine dehydrogenase, N-terminal domain; Dihydropyrimidine dehydrogenase, domain 4; Dihydropyrimidine dehydrogenase, domain 3; Dihydropyrimidine dehydrogenase, domain 2; Dihydropyrimidine dehydrogenase, C-terminal domain
3	View Details	[578..665]	PSI-BLAST	64.154902	Crystal Structure of Putidaredoxin Reductase from Pseudomonas putida

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
protein binding	3.07386271831775	bayes_pls_golite062009
binding	3.01297199434173	bayes_pls_golite062009
receptor activity	1.99923068102422	bayes_pls_golite062009
transmembrane receptor activity	1.94373624851094	bayes_pls_golite062009
molecular transducer activity	1.74126968021358	bayes_pls_golite062009
signal transducer activity	1.74126968021358	bayes_pls_golite062009
cytokine binding	1.17392704995902	bayes_pls_golite062009
growth factor binding	1.05300782116518	bayes_pls_golite062009
cytokine receptor activity	0.77377640884237	bayes_pls_golite062009
receptor binding	0.73866004523665	bayes_pls_golite062009
protein dimerization activity	0.674567146312744	bayes_pls_golite062009
protease binding	0.488597231764147	bayes_pls_golite062009
transcription regulator activity	0.48635527300904	bayes_pls_golite062009
enzyme binding	0.473046788409936	bayes_pls_golite062009
transcription activator activity	0.473002127561165	bayes_pls_golite062009
nucleic acid binding	0.408798856629207	bayes_pls_golite062009
identical protein binding	0.368517091723107	bayes_pls_golite062009
DNA binding	0.319941421296035	bayes_pls_golite062009

2

Term	Confidence	Notes
antioxidant activity	3.37477730756688	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	3.17769237742078	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	2.66213649027918	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	1.91752931331276	bayes_pls_golite062009
binding	1.75241039340546	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.6431755180135	bayes_pls_golite062009
succinate dehydrogenase (ubiquinone) activity	1.56913317166386	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	1.56913317166386	bayes_pls_golite062009
succinate dehydrogenase activity	1.54010881004951	bayes_pls_golite062009
protein binding	1.40812730845585	bayes_pls_golite062009
catalytic activity	1.35682608895635	bayes_pls_golite062009
thioredoxin-disulfide reductase activity	1.11021120187216	bayes_pls_golite062009
NADPH-adrenodoxin reductase activity	0.684108511779641	bayes_pls_golite062009
ion transmembrane transporter activity	0.230666982979064	bayes_pls_golite062009
cation transmembrane transporter activity	0.150449425695127	bayes_pls_golite062009
oxidoreductase activity	0.0180498293464497	bayes_pls_golite062009
disulfide oxidoreductase activity	0.0160065137614933	bayes_pls_golite062009

3

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle