Protein Overview: SRBP2_MOUSE

General Information:
Name(s) found:	SRBP2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|73661204\|ref\|NP_150087.1\| sterol regulatory element binding factor 2 [Mus musculus] [NCBI NR] gi\|166979751\|sp\|Q3U1N2.2\|SRBP2_MOUSE RecName: Full=Sterol regulatory element-binding protein 2; Short=SREBP-2; AltName: Full=Sterol regulatory element-binding transcription factor 2; Contains: RecName: Full=Processed sterol regulatory element-binding prot [NCBI NR] Sterol regulatory element-binding protein 2 OS=Mus musculus GN=Srebf2 PE=1 SV=2 [Swiss-Prot] sterol regulatory element binding factor 2 [HMR_022704.fasta] Tax_Id=10090 sterol regulatory element binding factor 2 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] sterol regulatory element binding factor 2 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2) [Contains: Processed sterol regulatory element-binding protein 2] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Srebf2 Isoform 1 of Sterol regulatory element-binding protein 2 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Srebf2 sterol regulatory element binding factor 2 [zeeyong.fasta] Tax_Id=10090 Gene_Symbol=Srebf2 sterol regulatory element binding factor 2 ENSMUSG00000022463 IPI00474598 IPI00761225 [IPIxENS.MOUSE_plus_REVERSE.fasta] sterol regulatory element-binding protein 2 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00474598.2\|SWISS-PROT:Q3U1N2-1\|TREMBL:Q8BPL7\|ENSEMBL:ENSMUSP00000023100\|REFSEQ:NP_150087 Tax_Id=10090 Gene_Symbol=Srebf2 Isoform 1 of Sterol regulatory element-binding protein 2 [ipi.MOUSE.fasta.20090209] Isoform 1 of Sterol regulatory element-binding protein 2 OS=Mus musculus GN=Srebf2 [011711_HMR.fasta] sp\|Q3U1N2\|SRBP2_MOUSE Sterol regulatory element-binding protein 2 OS=Mus musculus GN=Srebf2 PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	1130 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] dendrite [UNKNOWN] cytoplasm [UNKNOWN][IDA] membrane [IDA] integral to membrane [IEA] microsome [UNKNOWN] cytoplasmic vesicle [IEA] Golgi apparatus [IEA] endoplasmic reticulum [IEA]
Biological Process:	transcription [IEA] lipid metabolic process [IEA] cholesterol metabolic process [IEA] steroid metabolic process [IEA] positive regulation of transcription [UNKNOWN] response to hormone stimulus [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA] regulation of transcription [IDA] positive regulation of transcription via sterol regulatory element binding [IDA]
Molecular Function:	DNA binding [IDA] transcription factor activity [IDA] protein binding [IPI] transcription regulator activity [IEA] specific RNA polymerase II transcription factor activity [UNKNOWN] sequence-specific DNA binding [UNKNOWN] chromatin binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDESSELGVL ETMETLTELG DELTLGDIDE MLQFVSNQVG EFPDLFSEQL CSSFPGGGSN  60
   61 GGSGNNSSGR GNNGGATDPA VQRSFSQVPL STFSPSAASP QAPALQVKVS PTPPRATPVL 120
  121 QPRPQPQPQP PAQLQQQTVM ITPTFSTAPQ TRIIQQPLIY QNAATSFQVL QPQVQSLVTS 180
  181 PQVQPVTIQQ QVQTVQAQRV LTQTANGTLQ TLAPATVQTV AAPQVQQVPV LVQPQIIKTD 240
  241 SLVLTTLKTD GSPVMAAVQN PALTALTAPI QTAALQVPTL VGSNGTILTT MPVMMGQEKV 300
  301 PIKQVPGGVK QLDPPKEGER RTTHNIIEKR YRSSINDKII ELKDLVMGTD AKMHKSGVLR 360
  361 KAIDYIKYLQ QVNHKLRQEN MVLKLANQKN KLLKGIDLGS LVDSDVDLKI DDFNQNVLLM 420
  421 SPPASDSGSQ AGFSPYSIDS EPGSPLLDDA KVKDEPDSPP VALGMVDRSR ILLCVLTFLG 480
  481 LSFNPLTSLL QWGGAHNTDQ HPYSGSGRSV LSLESGAGGW FDWMVPTLLL WLVNGVIVLS 540
  541 VFVKLLVHGE PVIRPHSRPS VTFWRHRKQA DLDLAKGDFA AAAANLQTCL SVLGRALPTS 600
  601 RLDLACSLSW NVIRYSLQKL RLVRWLLKKV FQRWRATPAT AAGFEDEAKS SARDAALAYH 660
  661 RLHQLHITGK LPAGSACSDV HMALCAVNLA ECAEEKILPS TLIEIHLTAA MGLKTRCGGK 720
  721 LGFLASYFLN RAQSLCGPEH STVPDSLRWL CHPLGQKFFM ERSWSIKSAA KESLYCAQRS 780
  781 PADPIAQVHQ AFCKNLLERA VESLVKPQAK KKAGDQEEES CEFSSALEYL KLLHSFVDSV 840
  841 GFVTSPFSSS SVLRSALGPD VICRWWTSAV TMAISWLQGD DAAVRSRFTE VERVPKALEV 900
  901 TESPLVKAVF YTCRAMHASL SGKADGQQNS FCHCERASGH LWSSLNVSGT TSDPSLNHVI 960
  961 QLFTCDLLLS LRTALWQKQA SASQLLGETY HASGTELAGF QRDLGSLRRL AHSFRPAYRK1020
 1021 VFLHEATVRL MAGASPTRTH QLLEHSLRRR PTQNTKHGEV DTWPGQRERA TAILLACRHL1080
 1081 PLSFLSSPGQ RAVLLAEAAR TLEKVGDRRS CSDCQQMIVK LGGGTAIAAS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SRBP2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: