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Any process that activates or increases the frequency, rate or extent of the DNA-dependent transcription of a specific gene or genes. The process by which a sterol regulatory element binding protein (SREBP) mediates an increase in rate or extent of transcription of nuclear target genes in response to sterol depletion. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes. Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation. The specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter. In addition to RNA polymerase II and the general transcription factors, specific transcription requires one or more specific factors that bind to specific DNA sequences or interact with the general transcription machinery. A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of altered levels of one or more lipids, and resulting in the activation of transcription by SREBP. Any process that activates or increases the frequency, rate or extent of transcription from the RNA polymerase II promoter. The process by which a sterol regulatory element binding protein (SREBP) mediates an increase in rate or extent of transcription of nuclear target genes in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs in the promoters of target genes. Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter. Any process that modulates the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: positive regulation of transcription via sterol regulatory element binding
Acc: GO:0035104
Aspect: Biological Process
Desc: The process by which a sterol regulatory element binding protein (SREBP) mediates an increase in rate or extent of transcription of nuclear target genes in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs in the promoters of target genes.
Synonyms:
  • positive regulation of sterol regulatory element binding protein target gene transcription
  • sterol regulatory element binding protein target gene transcriptional activation
  • upregulation of sterol regulatory element binding protein target gene transcription
  • up-regulation of sterol regulatory element binding protein target gene transcription
  • activation of sterol regulatory element binding protein target gene transcription
  • up regulation of sterol regulatory element binding protein target gene transcription
  • SREBP target gene transcriptional activation
  • stimulation of sterol regulatory element binding protein target gene transcription
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0035104 - positive regulation of transcription via sterol regulatory element binding (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle