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Protein Overview: gi|36950991, gi|...

General Information:
Name(s) found: gi|36950991 [NCBI NR]
gi|119584618 [NCBI NR]
gi|119584617 [NCBI NR]
Description(s) found:
Found 23 descriptions.
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  • gi|36950991|ref|NP_003289.2| nuclear receptor subfamily 2, group C, member 2 [Homo sapiens] [NCBI NR]
  • gi|119584618|gb|EAW64214.1| nuclear receptor subfamily 2, group C, member 2, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119584617|gb|EAW64213.1| nuclear receptor subfamily 2, group C, member 2, isoform CRA_a [Homo sapiens] [NCBI NR]
    • Organism: Homo sapiens
    Length: 615 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSPSPRIQI ISTDSAVASP QRIQGSEPAS GPLSVFTSLN KEKIVTDQQT GQKIQIVTAV  60
   61 DASGSPKQQF ILTSPDGAGT GKVILASPET SSAKQLIFTT SDNLVPGRIQ IVTDSASVER 120
  121 LLGKTDVQRP QVVEYCVVCG DKASGRHYGA VSCEGCKGFF KRSVRKNLTY SCRSNQDCII 180
  181 NKHHRNRCQF CRLKKCLEMG MKMESVQSER KPFDVQREKP SNCAASTEKI YIRKDLRSPL 240
  241 IATPTFVADK DGARQTGLLD PGMLVNIQQP LIREDGTVLL ATDSKAETSQ GALGTLANVV 300
  301 TSLANLSESL NNGDTSEIQP EDQSASEITR AFDTLAKALN TTDSSSSPSL ADGIDTSGGG 360
  361 SIHVISRDQS TPIIEVEGPL LSDTHVTFKL TMPSPMPEYL NVHYICESAS RLLFLSMHWA 420
  421 RSIPAFQALG QDCNTSLVRA CWNELFTLGL AQCAQVMSLS TILAAIVNHL QNSIQEDKLS 480
  481 GDRIKQVMEH IWKLQEFCNS MAKLDIDGYE YAYLKAIVLF SPDHPGLTST SQIEKFQEKA 540
  541 QMELQDYVQK TYSEDTYRLA RILVRLPALR LMSSNITEEL FFTGLIGNVS IDSIIPYILK 600
  601 METAEYNGQI TGASL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..125] MSA 13.291997 View MSA. No confident structure predictions are available.
    2 View Details [126..217] PSI-BLAST 24.69897 Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
    3 View Details [218..318] deduced N/A No confident structure predictions are available.
    4 View Details [319..615] PSI-BLAST 51.69897 LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  5.53061626347066 bayes_pls_golite062009
  • DNA binding
    		•  4.92165988569962 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.78024150262074 bayes_pls_golite062009
  • transcription activator activity
    		•  4.53302455129434 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  4.11614358606713 bayes_pls_golite062009
  • transcription factor activity
    		•  4.0914094580319 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
    		•  3.89763470197726 bayes_pls_golite062009
  • binding
    		•  3.85318710398432 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.83878598697109 bayes_pls_golite062009
  • receptor activity
    		•  3.25980607692886 bayes_pls_golite062009
  • protein binding
    		•  3.21524787168952 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.88642387634609 bayes_pls_golite062009
  • signal transducer activity
    		•  2.88642387634609 bayes_pls_golite062009
  • transcription factor binding
    		•  2.68044489404568 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.38308182853979 bayes_pls_golite062009
  • retinoic acid receptor activity
    		•  2.35111225472682 bayes_pls_golite062009
  • steroid hormone receptor activity
    		•  2.30195937604451 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.73827483890179 bayes_pls_golite062009
  • nuclear hormone receptor binding
    		•  1.60419100774741 bayes_pls_golite062009
  • retinoic acid receptor binding
    		•  1.59968001933699 bayes_pls_golite062009
  • retinoid X receptor binding
    		•  1.45560845709347 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.34794228300778 bayes_pls_golite062009
  • promoter binding
    		•  1.28787959668198 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.23834725221597 bayes_pls_golite062009
  • receptor binding
    		•  1.04943671621651 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.995333369475571 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.797229273848179 bayes_pls_golite062009
  • hormone receptor binding
    		•  0.74373733735458 bayes_pls_golite062009
  • protein N-terminus binding
    		•  0.57701453824007 bayes_pls_golite062009
  • thyroid hormone receptor activity
    		•  0.49784404390361 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.47826452126899 bayes_pls_golite062009
  • lipid binding
    		•  0.475303782949439 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.45265806678057 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.42652610679613 bayes_pls_golite062009
  • transcription activator binding
    		•  0.2735140201748 bayes_pls_golite062009
  • ligand-regulated transcription factor activity
    		•  0.202197503742221 bayes_pls_golite062009
  • ecdysteroid hormone receptor activity
    		•  0.189811178379669 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.15737167800277 bayes_pls_golite062009
  • catalytic activity
    		•  0.106902059021677 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle