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Protein Overview: NFS1

General Information:
Name(s) found: NFS1 [HGNC (HUGO)]
Description(s) found:
Found 38 descriptions.
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  • NFS1 nitrogen fixation 1 homolog (S. cerevisiae) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 457 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLRAAWRRA AVAVTAAPGP KPAAPTRGLR LRVGDRAPQS AVPADTAAAP EVGPVLRPLY  60
   61 MDVQATTPLD PRVLDAMLPY LINYYGNPHS RTHAYGWESE AAMERARQQV ASLIGADPRE 120
  121 IIFTSGATES NNIAIKGVAR FYRSRKKHLI TTQTEHKCVL DSCRSLEAEG FQVTYLPVQK 180
  181 SGIIDLKELE AAIQPDTSLV SVMTVNNEIG VKQPIAEIGR ICSSRKVYFH TDAAQAVGKI 240
  241 PLDVNDMKID LMSISGHKIY GPKGVGAIYI RRRPRVRVEA LQSGGGQERG MRSGTVPTPL 300
  301 VVGLGAACEV AQQEMEYDHK RISKLSERLI QNIMKSLPDV VMNGDPKHHY PGCINLSFAY 360
  361 VEGESLLMAL KDVALSSGSA CTSASLEPSY VLRAIGTDED LAHSSIRFGI GRFTTEEEVD 420
  421 YTVEKCIQHV KRLREMSPLW EMVQDGIDLK SIKWTQH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..457] PSI-BLAST 95.522879 Cysteine desulfurase IscS

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  3.40354781002256 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  3.40354781002256 bayes_pls_golite062009
  • transferase activity
    		•  2.59075614411581 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  2.30133284041702 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • cysteine desulfurase activity
    		•  1.30923778688541 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • L-alanine:2-oxoglutarate aminotransferase activity
    		•  1.06988190956423 bayes_pls_golite062009
  • alanine-oxo-acid transaminase activity
    		•  1.06988190956423 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.977210827616757 bayes_pls_golite062009
  • binding
    		•  0.942651665520336 bayes_pls_golite062009
  • ligase activity
    		•  0.827063849687833 bayes_pls_golite062009
  • DNA binding
    		•  0.803965264969424 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.699955808682622 bayes_pls_golite062009
  • carbon-sulfur lyase activity
    		•  0.698312655247044 bayes_pls_golite062009
  • transcription factor activity
    		•  0.597417107954964 bayes_pls_golite062009
  • 5-aminolevulinate synthase activity
    		•  0.54326874956263 bayes_pls_golite062009
  • cystathionine gamma-lyase activity
    		•  0.505859361763689 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.50269055590758 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.27933426619091 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  0.271623203801431 bayes_pls_golite062009
  • O-phospho-L-serine:2-oxoglutarate aminotransferase activity
    		•  0.234399054481664 bayes_pls_golite062009
  • RNA binding
    		•  0.222777224430863 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.103986924428507 bayes_pls_golite062009
  • sulfurtransferase activity
    		•  0.0450490929307473 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.0254276656964899 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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