Protein Overview: kuz-PD

General Information:
Name(s) found:	kuz-PD / FBpp0111799 [FlyBase]
Description(s) found: Found 8 descriptions. SHOW ALL	The gene kuzbanian is referred to in FlyBase by the symbol Dmel\kuz (CG7147, FBgn0259984). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:13550141..13638238. It has the cytological map location 34C4-34C6. There is experimental evidence that it has the molecular function</span>: metalloendopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: heart morphogenesis; Notch receptor processing; border follicle cell migration; glial cell migration; skeletal muscle tissue development; muscle tissue development; pericardial cell differentiation; cardiac cell differentiation; lymph gland development; phagocytosis, engulfment. 81 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: organ system; nervous system; adult segment; peripheral nervous system; embryonic nervous system; thoracic segment; multi-cell-component structure; adult mesothoracic segment; external compound sense organ; commissure. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1256 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	cardiac cell differentiation [IMP] Notch receptor processing [IGI] muscle tissue development [IMP] border follicle cell migration [IMP] pericardial cell differentiation [IMP] glial cell migration [IMP] regulation of axon extension [TAS] heart morphogenesis [IMP] Notch signaling pathway [TAS] central nervous system development [TAS] phagocytosis, engulfment [IMP] skeletal muscle tissue development [IMP] lymph gland development [IMP] proteolysis [IEA]
Molecular Function:	zinc ion binding [IEA] metalloendopeptidase activity [IGI][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKCAFNIV FVSIIFIIIV NGYAKDISGV KRGECSVSNA ENVLHKNGVR CHERLNEYIS  60
   61 HYETLNYDHE HIRASHNRAR RSVTKDQYVH LKFASHGRDF HLRLKRDLNT FSNKLDFYDS 120
  121 KGPIDVSTDH IYEGEVIGDR NSYVFGSIHN GVFEGKIITE RDAYYVEHAK HYFPTNRTAT 180
  181 TTPPSTSTTS SATTATKSTQ PTRPLAKSNT STTAVNSKTE NFIKKIAEST TTSQQLPEYT 240
  241 ESSSSSTTTF PPTTEYFEDE KERNAEDELD FHSIIYKESH VEDAYENVRE GHVAGCGITD 300
  301 EVSQWMENIQ NSAVEELPEP MSKDYQKLHR KQLHKKSAPQ QQQQPHPPKK YISGDEDFKY 360
  361 PHQKYTKEAN FAEGAFYDPS TGRRLGSSAN VADWHQLVHE RVRRATDNGA GDRGSSGGSG 420
  421 RGREDNKNTC SLYIQTDPLI WRHIREGIAD HDRGRKYEVD EKTREEITSL IAHHVTAVNY 480
  481 IYRNTKFDGR TEHRNIRFEV QRIKIDDDSA CRNSYNGPHN AFCNEHMDVS NFLNLHSLED 540
  541 HSDFCLAYVF TYRDFTGGTL GLAWVASASG ASGGICEKYK TYTETVGGQY QSTKRSLNTG 600
  601 IITFVNYNSR VPPKVSQLTL AHEIGHNFGS PHDYPQECRP GGLNGNYIMF ASATSGDRPN 660
  661 NSKFSPCSIR NISNVLDVLV GNTKRDCFKA SEGAFCGNKI VESGEECDCG FNEEECKDKC 720
  721 CYPRLISEYD QSLNSSAKGC TRRAKTQCSP SQGPCCLSNS CTFVPTSYHQ KCKEETECSW 780
  781 SSTCNGTTAE CPEPRHRDDK TMCNNGTALC IRGECSGSPC LLWNMTKCFL TSTTLPHVSK 840
  841 RKLCDLACQD GNDTSTCRST SEFADKYNIQ KGGISLQPGS PCDNFQGYCD VFLKCRAVDA 900
  901 DGPLLRLKNL LLNRKTLQTV AEWIVDNWYL VVLMGVAFIV VMGSFIKCCA VHTPSSNPKK 960
  961 RRARRISETL RAPMNTLRRM QRHPNQRGAG PRSIPPPAHE AQHYSRGGDG RGGGGGGGGR1020
 1021 HGGSRSHHQQ HPHDWDRHQG GHSIVPLPTG GSHSSRNSAA NQARRSDGRG PRSTSSGRPQ1080
 1081 AIASGSGAAS GAARSHGGYG AEQAIPGSIG GGVQAAISSG GVVARAQLPL PLPPPNGQQQ1140
 1141 MQQQQQLQLQ QPAISPQQQP QQAFYTPKEL PPRNKSRSSR TNNTSNTTTT TNSSTAAAGS1200
 1201 GSVSGPGSGA GSSSKSKSGK SAKAKDSKSQ KSQQANNSRS SSKEKGVKPV RRNIVY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: kuz-PD

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: