Protein Overview: VGFR4_DANRE

General Information:
Name(s) found:	VGFR4_DANRE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|50401555\|sp\|Q8AXB3.1\|VGFR4_DANRE RecName: Full=Vascular endothelial growth factor receptor kdr-like; AltName: Full=Vascular endothelial growth factor receptor 4; Short=VEGFR-4; AltName: Full=Protein-tyrosine kinase receptor flk-1; AltName: Full=Fetal l [NCBI NR] gi\|24181844\|gb\|AAN47136.1\|AF487829_1 flk1 [Danio rerio] [NCBI NR] gi\|169146090\|emb\|CAQ13438.1\| kinase insert domain receptor [Danio rerio] [NCBI NR] (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC 2.7.1.112) (VEGFR-2) (Receptor tyrosine kinase flk-1) [Swiss-Prot] Vascular endothelial growth factor receptor kdr-like OS=Danio rerio GN=kdrl PE=1 SV=1 [Swiss-Prot] Vascular endothelial growth factor receptor 2 precursor - Danio rerio (Zebrafish) (Brachydanio rerio) [Swiss-Prot] Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) - Brachydanio rerio (Zebrafish) (Danio rerio) [Swiss-Prot] flk1 [Danio rerio]gi\|50401555\|sp\|Q8AXB3\|VGR2_BRARE Vascular endothelial growth factor receptor 2 precursor (VEGFR-2) (Receptor tyrosine kinase flk-1) [nrdb_11152004_Chlamydomonas] Vascular endothelial growth factor receptor 2 precursor (VEGFR-2) (Receptor tyrosine kinase flk-1) [nr-271106-contam.fasta] flk1 [Danio rerio] [nr-271106-contam.fasta] RecName: Full=Vascular endothelial growth factor receptor kdr-like; AltName: Full=Fetal liver kinase 1; Short=FLK-1; AltName: Full=Kinase insert domain receptor-A; AltName: Full=Kinase insert domain receptor-like; AltName: Full=Protein-tyrosine kinase receptor flk-1; AltName: Full=Vascular endothelial growth factor receptor 4; Short=VEGFR-4; Flags: Precursor [NCBI_RefSeq_D_rerio_20120531_05-31-2012_reversed.fasta]
Organism:	Danio rerio
Length:	1302 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [IEA] membrane [IEA] integral to membrane [IEA]
Biological Process:	peptidyl-tyrosine phosphorylation [IDA][IEA] vascular endothelial growth factor receptor signaling pathway [IEA] thyroid gland development [IMP] blood vessel development [IMP] angiogenesis [IEA][IGI][IMP] multicellular organismal development [IEA] cell differentiation [IEA] transmembrane receptor protein tyrosine kinase signaling pathway [IEA] artery morphogenesis [IMP] embryonic heart tube development [IMP] protein amino acid phosphorylation [IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein tyrosine kinase activity [IDA][IEA] growth factor binding [IEA] protein binding [IEA][IPI] transmembrane receptor protein tyrosine kinase activity [IEA] vascular endothelial growth factor receptor activity [IEA] protein kinase activity [IEA] transferase activity [IEA] receptor activity [IEA] kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPLKTSVKA FFTLHVLFSC ISHGLVEGSR LPDPQLLPDG DTHLQHVGGT LTLICRGSTA  60
   61 LHWRLASRNV SSVRIESCEE RLHKHCSKLV IHNLRHNDTG IYSCSHKKSS DHEVSTYVFV 120
  121 KDPHHPFVEA YSLPHPLFAY RNDPYFVVPC RTTYPNQNVI LETQMNPMAD DVKRGVQWDP 180
  181 KKGFTVPLKP YDSYHLITCL TRVDNAEFSS VYLLKRLTME IKNLAIEPER PRVLVGDTLI 240
  241 LNCSAETTYN GRIHFEWEFH KERINRTHHF STTPVQLAQI MVMSKALIVP NVTMEDKGTY 300
  301 TCTGSIEFKK LQMSTKVIVY EHPFLNVTHN KRKFTSTVEG RRVQFEPRVN AVPAPDRVLW 360
  361 YKDGVAISEN STCYETAGYN LTIKQVRQKD AGIFTIALSN QERGLYRNIS YKLEVRVKPK 420
  421 IFEEDVAPAG PQTFRYDQRH KLTCTAFGIP MPNITWFWQP CDPSANLTEC KLYTDPLPIE 480
  481 NVDDHFPQNP IKDVNSKVGL LKSKNRTIST LVVKTANVSG VYSCTARNEL GNRTMRIPFY 540
  541 VDDHPQPFEI EPSTAVAGDD ITLTCRGTRY LYDRLTWYDP LGHKVPKDET TLRIEPYTIS 600
  601 LSIKLPNVSR NHTLGYECQA LKINTNKVVN VTSALTIDER QGPWLMQNLT NQDVNSSSTL 660
  661 TLACLAYGVP APFITWYKDK TPVTEGPGIT LKDDGTLIIE RVKKDDEGIY ECRASNDGGE 720
  721 AKTSAVITVV GEDGKPNIEV IILVSTGAAA TFLWIMLILF IRKLRKPSSA DLKTGYLSII 780
  781 MDPEQMPLDE QCDRLPYDSN KWEFPQDRLR LGKTLGHGAF GKVVEASAFG IDKISTCKTV 840
  841 AVKMLKVGAT NNEWRALMSE LKILIHIGHH LNVVNLLGAC TKRGGPLMII VEFCKYGNLS 900
  901 NYLRSKRGDF VVYKSQDGKA VRSSSGCDLS ELIKRRLESV ASTGSSASSG FIEDKSYCDS 960
  961 EEEEEEQEDL YKKVLTLEDL ICYSFQVAKG MEFLASRKCI HRDLAARNIL LSENNVVKIC1020
 1021 DFGLARDVYK DPDYVRKGDA RLPLKWMAPE AIFDKIYTTQ SDVWSFGVLM WEIFSLGASP1080
 1081 YPGLHIDEEF CCRLKEGTRM KAPEYSSSEI YQTMLDCWHG EPSQRPTFTE LVERLGDLLQ1140
 1141 ASVQQEGKHY IPINTALLTK ADPSNQSPTE ETSTRPVSLR DSGTAWNIKI RPESVKTFDE1200
 1201 VILENGTNKI HEGGQSDSGI GLSSDDLKTL KRLESLARPR SFMSRAMKRK SKESVLLEGE1260
 1261 MDKYPPLVPS LSLEDSSLDS EMECHSPPPD YNYVVRYSTP PV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: VGFR4_DANRE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: