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Protein Overview: SYK2_ECOLI

General Information:
Name(s) found: SYK2_ECOLI [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • (P0A8N5) Lysyl-tRNA synthetase, heat inducible (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS) [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 504 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEQETRGANE AIDFNDELRN RREKLAALRQ QGVAFPNDFR RDHTSDQLHE EFDAKDNQEL  60
   61 ESLNIEVSVA GRMMTRRIMG KASFVTLQDV GGRIQLYVAR DSLPEGVYND QFKKWDLGDI 120
  121 IGARGTLFKT QTGELSIHCT ELRLLTKALR PLPDKFHGLQ DQEVRYRQRY LDLIANDKSR 180
  181 QTFVVRSKIL AAIRQFMVAR GFMEVETPMM QVIPGGASAR PFITHHNALD LDMYLRIAPE 240
  241 LYLKRLVVGG FERVFEINRN FRNEGISVRH NPEFTMMELY MAYADYHDLI ELTESLFRTL 300
  301 AQEVLGTTKV TYGEHVFDFG KPFEKLTMRE AIKKYRPETD MADLDNFDAA KALAESIGIT 360
  361 VEKSWGLGRI VTEIFDEVAE AHLIQPTFIT EYPAEVSPLA RRNDVNPEIT DRFEFFIGGR 420
  421 EIGNGFSELN DAEDQAERFQ EQVNAKAAGD DEAMFYDEDY VTALEYGLPP TAGLGIGIDR 480
  481 MIMLFTNSHT IRDVILFPAM RPQK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..504] PSI-BLAST 159.0 Lysyl-tRNA synthetase (LysRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • lysine-tRNA ligase activity
    		•  11.0047124677093 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.89468709683036 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.89468709683036 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.88410036819636 bayes_pls_golite062009
  • ligase activity
    		•  6.92073480193262 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  5.29805946490109 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  3.80084837437429 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  3.4145644216516 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.90150581291897 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  2.61548498770105 bayes_pls_golite062009
  • structural molecule activity
    		•  2.54582212334303 bayes_pls_golite062009
  • proline-tRNA ligase activity
    		•  2.52223115725965 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  2.46505535069103 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  2.18642354927 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  1.82594054955281 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  1.72215103383322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.67362693618722 bayes_pls_golite062009
  • binding
    		•  1.54403712698597 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.48056625237411 bayes_pls_golite062009
  • DNA binding
    		•  1.44496421928708 bayes_pls_golite062009
  • translation initiation factor activity
    		•  1.27539679024898 bayes_pls_golite062009
  • transcription factor activity
    		•  0.825973629967327 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.77755643935497 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.702449673647117 bayes_pls_golite062009
  • nuclease activity
    		•  0.29926900436997 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle