Protein Overview: SIR2_DANRE

General Information:
Name(s) found:	SIR2_DANRE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|41054575\|ref\|NP_955890.1\| sirtuin 2 [Danio rerio] [NCBI NR] gi\|38258425\|sp\|Q7ZVK3.1\|SIRT2_DANRE RecName: Full=NAD-dependent deacetylase sirtuin-2 [NCBI NR] gi\|28278385\|gb\|AAH45510.1\| Sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) [Danio rerio] [NCBI NR] NAD-dependent deacetylase sirtuin-2 OS=Danio rerio GN=sirt2 PE=2 SV=1 [Swiss-Prot] NAD-dependent deacetylase sirtuin-2 (EC 3.5.1.-) - Brachydanio rerio (Zebrafish) (Danio rerio) [Swiss-Prot] NAD-dependent protein deacetylase sirtuin-2 OS=Danio rerio GN=sirt2 PE=2 SV=1 [Swiss-Prot] (Q7ZVK3) NAD-dependent deacetylase sirtuin 2 (EC 3.5.1.-) [Swiss-Prot] sirtuin 2 (silent mating type information regulation 2, homolog) 2; sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae); wu:fb57d05 [071204_hmrz_cont.fasta] sirtuin 2 (silent mating type information regulation 2, homolog) 2 [Danio rerio]gi\|28278385\|gb\|AAH45510.1\| Sirtuin 2 (silent mating type information regulation 2, homolog) 2 [Danio rerio]gi\|38258425\|sp\|Q7ZVK3\|SIR2_BRARE NAD-dependent deacetylase sirtuin [nrdb_11152004_Chlamydomonas] Sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) [Danio rerio] [nr-271106-contam.fasta] NAD-dependent deacetylase sirtuin-2 [nr-271106-contam.fasta] sirtuin 2 [Danio rerio] [nr-271106-contam.fasta] NAD-dependent deacetylase sirtuin-2 [Danio rerio] [NCBI-RefSeq_D_rerio_na_08-30-2010_reversed.fasta] NAD-dependent protein deacetylase sirtuin-2 [Danio rerio] [NCBI_RefSeq_D_rerio_20120531_05-31-2012_reversed.fasta] RecName: Full=NAD-dependent protein deacetylase sirtuin-2; AltName: Full=Regulatory protein SIR2 homolog 2; AltName: Full=SIR2-like protein 2 [NCBI_RefSeq_D_rerio_20120531_05-31-2012_reversed.fasta]
Organism:	Danio rerio
Length:	379 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA]
Biological Process:	protein amino acid deacetylation [IEA] chromatin silencing [IEA] regulation of transcription [IEA]
Molecular Function:	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [IEA] zinc ion binding [IEA] NAD or NADH binding [IEA] metal ion binding [IEA] NAD binding [IEA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEEVSKRVE EEADTPGLEG QSDDSSDEGD ASGDTEMDFL RSLFSRTLGL SPGDKVLDEL  60
   61 TLDSVARYIL SGKCKNIICM VGAGISTSAG IPDFRSPGTG LYANLQKYNL PYPEAIFQID 120
  121 YFKKHPEPFF ALARELYPGQ FKPTVYHYFI KMLKDKGLLR RCYSQNIDTL ERVAGLEGED 180
  181 LIEAHGTFHT SHCVSFLCRK EYSMDWMKNQ IFSEEIPKCD SCGSLVKPDI VFFGESLPSR 240
  241 FFTSMKADFP QCDLLIIMGT SLQVQPFASL VSRVSNRCPR LLINMEKTGQ SEFGMGLFSF 300
  301 GGGMDFDSDK AYRDVAHLST CDDGCMTLAE LLGWKKELEE MVKREHALID SKDAKKTDKE 360
  361 ASQSSKSAVA EAEKTDKTE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: SIR2_DANRE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: