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Protein Overview: PDGFA_RAT

General Information:
Name(s) found: PDGFA_RAT [Swiss-Prot]
Description(s) found:
Found 10 descriptions.
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  • Platelet-derived growth factor subunit A OS=Rattus norvegicus GN=Pdgfa PE=2 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 204 amino acids

    Gene Ontology:
    Cellular Component: platelet alpha granule lumen [UNKNOWN]
    extracellular space [UNKNOWN][IEA]
    microvillus [UNKNOWN][IEA]
    membrane [IEA]
    extracellular region [UNKNOWN][IEA]
    cellular_component [ND]
    cell surface [UNKNOWN][IEA]
    Biological Process: regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling [UNKNOWN][IEA]
    negative chemotaxis [UNKNOWN][IEA]
    inner ear development [IEP]
    cell projection assembly [UNKNOWN][IEA]
    positive regulation of cell proliferation [UNKNOWN][IMP]
    transforming growth factor beta receptor signaling pathway [IEP]
    response to wounding [UNKNOWN]
    positive regulation of DNA replication [UNKNOWN][IEA]
    skin development [UNKNOWN][IEA]
    lung alveolus development [UNKNOWN][IEA]
    regulation of peptidyl-tyrosine phosphorylation [UNKNOWN][IEA]
    response to retinoic acid [IEP]
    wound healing [IEP]
    response to hypoxia [IEP]
    hair follicle development [UNKNOWN][IEA]
    positive regulation of cell division [IEA]
    angiogenesis [UNKNOWN][IEA]
    positive regulation of fibroblast proliferation [UNKNOWN][IEA]
    negative regulation of phosphatidylinositol biosynthetic process [UNKNOWN][IEA]
    response to inorganic substance [IEP]
    regulation of smooth muscle cell migration [UNKNOWN][IEA]
    response to organic substance [IEP]
    platelet-derived growth factor receptor signaling pathway [UNKNOWN][IEA]
    positive regulation of mesenchymal cell proliferation [UNKNOWN][IEA]
    organ morphogenesis [UNKNOWN][IEA]
    response to drug [IEP]
    response to estradiol stimulus [IEP]
    negative regulation of platelet activation [UNKNOWN][IEA]
    actin cytoskeleton organization [UNKNOWN][IEA]
    positive regulation of cell migration [UNKNOWN][IEA]
    Molecular Function: growth factor activity [TAS]
    protein homodimerization activity [UNKNOWN][IEA]
    platelet-derived growth factor receptor binding [UNKNOWN][IEA]
    collagen binding [UNKNOWN][IEA]
    protein heterodimerization activity [UNKNOWN][IEA]
    cell surface binding [UNKNOWN][IEA]
    platelet-derived growth factor binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTWACLLLL GCGYLAHALA EEAEIPRELI ERLARSQIHS IRDLQRLLEI DSVGAEDALE  60
   61 TNLRAHGSHT VKHVPEKRPV PIRRKRSIEE AIPAVCKTRT VIYEIPRSQV DPTSANFLIW 120
  121 PPCVEVKRCT GCCNTSSVKC QPSRVHHRSV KVAKVEYVRK KPKLKEVQVR LEEHLECACA 180
  181 TSNLNPDHRE EETGRRRESG KKRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle