Protein Overview: D2R-PD

General Information:
Name(s) found:	D2R-PD / FBpp0099565 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|62473879\|ref\|NP_001014757.1\| dopamine 2-like receptor, isoform D [Drosophila melanogaster] [NCBI NR] gi\|61677851\|gb\|AAX52463.1\| dopamine 2-like receptor, isoform D [Drosophila melanogaster] [NCBI NR] gi\|48428075\|sp\|Q8IS44.1\|DRD2L_DROME RecName: Full=Dopamine D2-like receptor; Short=DD2R [NCBI NR] gi\|23320917\|gb\|AAN15956.1\| dopamine 2-like receptor DD2R-506 [Drosophila melanogaster] [NCBI NR] Dopamine D2-like receptor OS=Drosophila melanogaster GN=Dop2R PE=2 SV=1 [Swiss-Prot] (Q8IS44) Dopamine D2-like receptor (DD2R) [Swiss-Prot] The gene Dopamine 2-like receptor is referred to in FlyBase by the symbol Dmel\D2R (CG33517, FBgn0053517). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19898715..19922226. It has the cytological map location 19A4. There is experimental evidence that it has the molecular function</span>: dopamine receptor activity, coupled via Gi/Go; dopamine receptor activity. There is experimental evidence that it is involved in the biological process</span>: dopamine receptor signaling pathway. 4 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] dopamine 2-like receptor DD2R-506 [Drosophila melanogaster]gi\|48428075\|sp\|Q8IS44\|D2DR_DROME Dopamine D2-like receptor (DD2R) [nrdb_11152004_Chlamydomonas] type=protein; loc=X:complement(19901052..19901263,19901374..19901474,19901663..19901797,19904358..19904656,19905163..19905415,19905488..19905597,19920738..19920928,19921784..19922003); ID=FBpp0099565; name=D2R-PD; parent=FBgn0053517,FBtr0091462; dbxref=Fl [fly-100309-contam.fasta] Dopamine 2-like receptor CG33517-PD, isoform D [Drosophila melanogaster] [nr-271106-contam.fasta] Dopamine D2-like receptor (DD2R) [nr-271106-contam.fasta] CG33517-PD, isoform D [Drosophila melanogaster] [nr-271106-contam.fasta] dopamine 2-like receptor DD2R-506 [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=X:complement(19901052..19901263,19901374..19901474,19901663..19901797,19904358..19904656,19905163..19905415,19905488..19905597,19920738..19920928,19921784..19922003); ID=FBpp0099565; name=D2R-PD; parent=FBgn0053517,FBtr0091462; dbxref=FlyBase_Annotation_IDs:CG33517-PD,FlyBase:FBpp0099565,GB_protein:AAX52463.1,REFSEQ:NP_001014757,GB_protein:AAX52463; MD5=d3bf2a38a8c3d320ea36d279fefa8e04; length=506; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=X:complement(19901052..19901263,19901374..19901474,19901663..19901797,19904358..19904656,19905163..19905415,19905488..19905597,19920738..19920928,19921784..19922003); ID=FBpp0099565; name=D2R-PD; parent=FBgn0053517,FBtr0091462; dbxref=FlyBase_Annotation_IDs:CG33517-PD,FlyBase:FBpp0099565,GB_protein:AAX52463.1,REFSEQ:NP_001014757,GB_protein:AAX52463; MD5=d3bf2a38a8c3d320ea36d279fefa8e04; length=506; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Dopamine D2-like receptor OS=Drosophila melanogaster GN=D2R PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=X:complement(19901052..19901263,19901374..19901474,19901663..19901797,19904358..19904656,19905163..19905415,19905488..19905597,19920738..19920928,19921784..19922003); ID=FBpp0099565; name=D2R-PD; parent=FBgn0053517,FBtr0091462; dbxref=FlyBase_Annotation_IDs:CG33517-PD,FlyBase:FBpp0099565,GB_protein:AAX52463.1,REFSEQ:NP_001014757,GB_protein:AAX52463,FlyMine:FBpp0099565,modMine:FBpp0099565; MD5=d3bf2a38a8c3d320ea36d279fefa8e04; length=506; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
Organism:	Drosophila melanogaster
Length:	506 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [ISS][NAS]
Biological Process:	G-protein coupled receptor protein signaling pathway [ISS] dopamine receptor signaling pathway [IDA][ISS]
Molecular Function:	dopamine receptor activity [IDA][ISS] G-protein coupled receptor activity [ISS] dopamine receptor activity, coupled via Gi/Go [IDA][NAS] G-protein coupled amine receptor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLLENFNDY FPNYNGSTVS GTSTIAPGVA ITGSRGSGLL LEQNLTGLYL DGYRLNCTNE  60
   61 TLNLTDSCGE LRVVDHNYWA LILILFPILT LFGNILVILS VCRERSLQTV TNYFIVSLAI 120
  121 ADLLVAVVVM PFAVYFLVNG AWALPDVVCD FYIAMDVICS TSSIFNLVAI SIDRYIAVTQ 180
  181 PIKYAKHKNS RRVCLTILLV WAISAAIGSP IVLGLNNTPN REPDVCAFYN ADFILYSSLS 240
  241 SFYIPCIIMV FLYWNIFKAL RSRARKQRAA RKPHLSELTG GSVIENIAQT RRLAETALDS 300
  301 SRHASRILPD EAATNTASGS NEEEDENAIS PDIDDCHVIV NDKSTEFMLA TVVEETGNVA 360
  361 MKPLSFVRYG VQEAMTLARN DSTLSTTSKT SSRKDKKNSQ ASRFTIYKVH KASKKKREKS 420
  421 SAKKERKATK TLAIVLGVFL FCWLPFFSCN IMDAMCAKFK KDCRPGLTAY MMTTWLGYIN 480
  481 SFVNPVIYTI FNPEFRKAFK KIMHMG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..340]	PSI-BLAST	38.522879	Rhodopsin
2	View Details	[341..506]	FFAS03	5.83	Rhodopsin

Protein Overview: D2R-PD

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: