Protein Overview: ARRB2_RAT

General Information:
Name(s) found:	ARRB2_RAT [Swiss-Prot]
Description(s) found: Found 21 descriptions. SHOW ALL	Beta-arrestin-2 OS=Rattus norvegicus GN=Arrb2 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	410 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] cytoplasm [UNKNOWN][IEA] postsynaptic membrane [IDA] coated pit [IEA] cytoplasmic vesicle [UNKNOWN] cytoplasmic membrane-bounded vesicle [IEA] intracellular [UNKNOWN] plasma membrane [UNKNOWN][IEA]
Biological Process:	G-protein coupled receptor protein signaling pathway [IDA] negative regulation of NF-kappaB transcription factor activity [UNKNOWN] protein transport [IEA] transforming growth factor beta receptor signaling pathway [UNKNOWN] transcription from RNA polymerase II promoter [UNKNOWN] G-protein coupled receptor internalization [UNKNOWN] desensitization of G-protein coupled receptor protein signaling pathway by arrestin [UNKNOWN][TAS] regulation of G-protein coupled receptor protein signaling pathway [UNKNOWN][IDA] endocytosis [IDA] negative regulation of natural killer cell mediated cytotoxicity [UNKNOWN] sensory perception [IEA] cell chemotaxis [UNKNOWN] negative regulation of signal transduction [IEA] regulation of protein amino acid phosphorylation [UNKNOWN] regulation of cAMP biosynthetic process [TAS] positive regulation of ERK1 and ERK2 cascade [UNKNOWN] negative regulation of protein ubiquitination [UNKNOWN] receptor internalization [UNKNOWN] regulation of cAMP catabolic process [TAS] protein ubiquitination [UNKNOWN]
Molecular Function:	G-protein-coupled receptor binding [UNKNOWN][TAS] protein domain specific binding [IPI] angiotensin receptor binding [UNKNOWN] protein binding [UNKNOWN][IPI] ubiquitin protein ligase binding [UNKNOWN] clathrin binding [TAS] receptor binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEKPGTRVF KKSSPNCKLT VYLGKRDFVD HLDKVDPVDG VVLVDPDYLK DRKVFVTLTC  60
   61 AFRYGREDLD VLGLSFRKDL FIATYQAFPP MPNPPRPPTR LQDRLLKKLG QHAHPFFFTI 120
  121 PQNLPCSVTL QPGPEDTGKA CGVDFEIRAF CAKSIEEKSH KRNSVRLIIR KVQFAPETPG 180
  181 PQPSAETTRH FLMSDRRSLH LEASLDKELY YHGEPLNVNV HVTNNSAKTV KKIRVSVRQY 240
  241 ADICLFSTAQ YKCPVAQLEQ DDQVSPSSTF CKVYTITPLL SDNREKRGLA LDGQLKHEDT 300
  301 NLASSTIVKE GANKEVLGIL VSYRVKVKLV VSRGGDVSVE LPFVLMHPKP HDHITLPRPQ 360
  361 SAPREIDIPV DTNLIEFDTN YATDDDIVFE DFARLRLKGM KDDDCDDQFC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: ARRB2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: