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Protein Overview: acr-20

General Information:
Name(s) found: acr-20 / CE36709 [WormBase]
Description(s) found:
Found 13 descriptions.
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  • WBGene00000059 locus:acr-20 status:Confirmed UniProt:Q7JKI4 protein_id:CAE46678.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 511 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic membrane [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: ion transport [IEALink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: neurotransmitter receptor activity [IEALink to PubMed article]
    extracellular ligand-gated ion channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKSPIEVH FSMELYQIIS VNEPQQFLML NAWVVERWTD RLLGWDPEKF GNVTEIMLPH  60
   61 HFIWLPDTTL YNSLVMKDDE NRRLLHAKVT TLGEGNGAFI ELLYPTIYKL SCLLNLRFFP 120
  121 FDVQSCRLLF GSWTFDNTKI DYFAFNESQA IGTTNCIENE GWNVLSTSVI RHENKYDCCP 180
  181 NNYTLLEFRL TIQRKPLYYI INLIIPTSII TFISIIGFFS TSSINEPREE KITLGITTLL 240
  241 SMSILIFMVS DKMPSTSSFI PLIGLFYTSM ILLISFSTIC SSVVIYVQKQ GNLGNPPSKN 300
  301 FMNIARAVNR FIRMEMPLIM KQAYAQKARE EKLRRQQMGR KQSLWTRVYK LAREQALRKT 360
  361 SQNSSKFNEV LTPEKLIDNG GKRCTINKDV TCISDSGIVA MGVPTLASED DDQDVSLLEL 420
  421 ETTPTPAMQR PTRLHKASTC GSFDSMMFRQ IEVPVSPRTA RNLAEIEYDW LAALLERIFL 480
  481 ITFLFIFVLT SIGINLIGFF YWWMAPDTVR V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..194] PSI-BLAST 68.39794 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
    2 View Details [195..511] PSI-BLAST 37.30103 Acetylcholine receptor protein, delta chain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • extracellular ligand-gated ion channel activity
    		•  6.56684020745942 bayes_pls_golite062009
  • excitatory extracellular ligand-gated ion channel activity
    		•  6.56684020745942 bayes_pls_golite062009
  • acetylcholine binding
    		•  6.52442204852986 bayes_pls_golite062009
  • nicotinic acetylcholine-activated cation-selective channel activity
    		•  6.36289790201154 bayes_pls_golite062009
  • acetylcholine receptor activity
    		•  6.18186125255445 bayes_pls_golite062009
  • amine binding
    		•  5.41519146716044 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  4.11436828514898 bayes_pls_golite062009
  • neurotransmitter binding
    		•  3.8955866963605 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  3.89042942026915 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  3.89042942026915 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  3.85109091742077 bayes_pls_golite062009
  • channel activity
    		•  3.85109091742077 bayes_pls_golite062009
  • gated channel activity
    		•  3.78736801121715 bayes_pls_golite062009
  • ion channel activity
    		•  3.74897051183521 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  3.71266288521973 bayes_pls_golite062009
  • cation channel activity
    		•  3.63600692930143 bayes_pls_golite062009
  • signal transducer activity
    		•  2.79604294798446 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.79604294798446 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.68988479891625 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.2664383168765 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.15975795305845 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.86141735260141 bayes_pls_golite062009
  • binding
    		•  1.79555479138162 bayes_pls_golite062009
  • receptor activity
    		•  1.7530052047317 bayes_pls_golite062009
  • chloride channel regulator activity
    		•  1.70228013722122 bayes_pls_golite062009
  • neurotransmitter receptor activity
    		•  1.66164195684481 bayes_pls_golite062009
  • channel regulator activity
    		•  1.19940273232477 bayes_pls_golite062009
    		• 1.14757191423748 bayes_pls_golite062009
  • transporter activity
    		•  0.768184565846134 bayes_pls_golite062009
  • beta-amyloid binding
    		•  0.60757966423936 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.601789813334198 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.405772730772208 bayes_pls_golite062009
  • protein binding
    		•  0.174311879345146 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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