| Protein: | acr-20 |
| Organism: | Caenorhabditis elegans |
| Length: | 511 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-20.
| Description | E-value | Query Range |
Subject Range |
|
|
388.0 | [0..2] | [508..44] |
|
Region A: Residues: [1-194] |
1 11 21 31 41 51
| | | | | |
1 MGKKSPIEVH FSMELYQIIS VNEPQQFLML NAWVVERWTD RLLGWDPEKF GNVTEIMLPH 60
61 HFIWLPDTTL YNSLVMKDDE NRRLLHAKVT TLGEGNGAFI ELLYPTIYKL SCLLNLRFFP 120
121 FDVQSCRLLF GSWTFDNTKI DYFAFNESQA IGTTNCIENE GWNVLSTSVI RHENKYDCCP 180
181 NNYTLLEFRL TIQR
|
| Detection Method: |  |
| Confidence: | 68.39794 |
| Match: | 2bg9E |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [195-511] |
1 11 21 31 41 51
| | | | | |
1 KPLYYIINLI IPTSIITFIS IIGFFSTSSI NEPREEKITL GITTLLSMSI LIFMVSDKMP 60
61 STSSFIPLIG LFYTSMILLI SFSTICSSVV IYVQKQGNLG NPPSKNFMNI ARAVNRFIRM 120
121 EMPLIMKQAY AQKAREEKLR RQQMGRKQSL WTRVYKLARE QALRKTSQNS SKFNEVLTPE 180
181 KLIDNGGKRC TINKDVTCIS DSGIVAMGVP TLASEDDDQD VSLLELETTP TPAMQRPTRL 240
241 HKASTCGSFD SMMFRQIEVP VSPRTARNLA EIEYDWLAAL LERIFLITFL FIFVLTSIGI 300
301 NLIGFFYWWM APDTVRV
|
| Detection Method: | |
| Confidence: | 37.30103 |
| Match: | 1oedC |
| Description: | Acetylcholine receptor protein, delta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| extracellular ligand-gated ion channel activity | 6.56684020745942 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 6.56684020745942 | bayes_pls_golite062009 |
| acetylcholine binding | 6.52442204852986 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 6.36289790201154 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 6.18186125255445 | bayes_pls_golite062009 |
| amine binding | 5.41519146716044 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 4.11436828514898 | bayes_pls_golite062009 |
| neurotransmitter binding | 3.8955866963605 | bayes_pls_golite062009 |
| ligand-gated channel activity | 3.89042942026915 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 3.89042942026915 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 3.85109091742077 | bayes_pls_golite062009 |
| channel activity | 3.85109091742077 | bayes_pls_golite062009 |
| gated channel activity | 3.78736801121715 | bayes_pls_golite062009 |
| ion channel activity | 3.74897051183521 | bayes_pls_golite062009 |
| substrate-specific channel activity | 3.71266288521973 | bayes_pls_golite062009 |
| cation channel activity | 3.63600692930143 | bayes_pls_golite062009 |
| signal transducer activity | 2.79604294798446 | bayes_pls_golite062009 |
| molecular transducer activity | 2.79604294798446 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.68988479891625 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.2664383168765 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.15975795305845 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.86141735260141 | bayes_pls_golite062009 |
| binding | 1.79555479138162 | bayes_pls_golite062009 |
| receptor activity | 1.7530052047317 | bayes_pls_golite062009 |
| chloride channel regulator activity | 1.70228013722122 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 1.66164195684481 | bayes_pls_golite062009 |
| channel regulator activity | 1.19940273232477 | bayes_pls_golite062009 |
| 1.14757191423748 | bayes_pls_golite062009 | |
| transporter activity | 0.768184565846134 | bayes_pls_golite062009 |
| beta-amyloid binding | 0.60757966423936 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.601789813334198 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.405772730772208 | bayes_pls_golite062009 |
| protein binding | 0.174311879345146 | bayes_pls_golite062009 |
