Protein Overview: unc-73

General Information:
Name(s) found:	unc-73 / CE36937 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006805 locus:unc-73 status:Confirmed UniProt:C4ALD5 protein_id:CCD63884.1 [WormBase] gi\|71987174\|ref\|NP_001021501.1\| UNCoordinated family member (unc-73) [Caenorhabditis elegans] [NCBI NR] gi\|50058059\|gb\|AAT68892.1\| Uncoordinated protein 73, isoform f [Caenorhabditis elegans] [NCBI NR] gi\|227452775\|gb\|ACP34144.1\| Uncoordinated protein 73, isoform i [Caenorhabditis elegans] [NCBI NR] Uncoordinated protein 73, isoform f [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] CE36937 WBGene00006805 locus:unc-73 status:Confirmed TR:Q6BEW2 protein_id:AAT68892.1 [wormpep150.fasta] 36937 WBGene00006805 locus:unc-73 status:Partially_confirmed protein_id:AAT68892.1 [wormpep130-phg-ecoli-orf-rand.fasta] CE36937 WBGene00006805 locus:unc-73 status:Partially_confirmed TR:Q6BEW2 protein_id:AAT68892.1 [wormpep132.fasta] 36937 WBGene00006805 locus:unc-73 status:Confirmed TR:Q6BEW2 protein_id:AAT68892.1 [wormpep150-phg-orf-ecoli-rand.fasta] CE36937 WBGene00006805 locus:unc-73 status:Confirmed UniProt:Q6BEW2_CAEEL protein_id:AAT68892.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE36937 WBGene00006805 locus:unc-73 status:Confirmed UniProt:Q6BEW2_CAEEL protein_id:AAT68892.1\| [wormORF-contam.fasta] UNCoordinated family member (unc-73) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE36937 WBGene00006805 locus:unc-73 status:Confirmed UniProt:C4ALD5 protein_id:ACP34144.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE36937 WBGene00006805 locus:unc-73 status:Confirmed UniProt:C4ALD5 protein_id:CCD63884.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] Isoform of O61528, Uncharacterized protein OS=Caenorhabditis elegans GN=unc-73 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	2140 amino acids
Gene Ontology:
Cellular Component:	axon [IDA] intracellular [IEA] proteinaceous extracellular matrix [IEA]
Biological Process:	Rac protein signal transduction [IC] male genitalia morphogenesis [IMP] regulation of Rho protein signal transduction [IEA] DNA repair [IEA] hermaphrodite genitalia development [IMP] regulation of locomotion [IMP] mesodermal cell migration [TAS] locomotion [IMP] embryonic development ending in birth or egg hatching [IMP][NAS] positive regulation of axon extension [IMP] cell adhesion [IEA] gamete generation [IMP] engulfment of apoptotic cell [IGI] blood coagulation [IEA] positive regulation of multicellular organism growth [IMP] regulation of vulval development [TAS] positive regulation of locomotion [IMP] neuron migration [TAS] locomotory behavior [IMP] nematode larval development [NAS] positive regulation of actin filament polymerization [IDA] oviposition [IMP ][TAS] cell migration [TAS]
Molecular Function:	guanyl-nucleotide exchange factor activity [IEA] Rho guanyl-nucleotide exchange factor activity [IEA] Rac guanyl-nucleotide exchange factor activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDYDGKMTM KAEDILHVLR DGIAVLPGGR CRAGQAVIVC PSREQPVNQD NLRNVFLYLF  60
   61 EVTSKMAREK GFLVVIDMRG KQTWTNVRHI LKALSSIESS STVQVFIIKP EKFWEKQKAQ 120
  121 MSLGTWDFEV EMISFESLIK IIDSSHLPKT VGGSYPYDHD EWLELRLDLE KWIWNITEIM 180
  181 EKLESVRREI CEGEQPVDVT TANAALKKSQ HAKNSIFNVP VEGIETEGNK IATRILKPSK 240
  241 GVKNPDLEAT TPYISNLTDS LRLLKGEVAK NWEVRQMELS KVYQQKQFER DAEHMIETLR 300
  301 PYKKACERSM GDVGGCANDV VRLSAEFEQF QIAVRGMEVS VKQVFDKENH LRTIGARNQI 360
  361 TDHVAARLAE EWHLVKELME RRSAVLHNAK EFFTSAQRYF AEVPRWTAQP GVNPNDVLFN 420
  421 QESLEEAIRK HDAFWAQVEE VYAQAYDDAS KVTRALKEAD AEDNVAREHS SRLQRAHKQL 480
  481 MEKWKERQVL LHHMLAMIAF ETDVRLVVDW LEQHGEPYLR RNIHIGENVN QARSFQRNHT 540
  541 NFQRVAANTY GNVQKLHQVY QDVTKSGSKI CDVDTMHGLM TDLSAKIEKF TKIENSRELL 600
  601 LRQSVLFHTH YKELTDWYGK MGEKYKDRRI DLTVPTCDKN KERFVLETDE TAQAYAMTID 660
  661 EGKTLIEMMQ RATRVFDVDY SASVAHIQLL ISDIEDKNTQ ISSEWSPRRT LLHIASKFAM 720
  721 FEQNQFEVLE QIKSWEVDMR EMAESDSFYD KADSVLPFHK DNQQQVRNAI ADIQKSAKEL 780
  781 SQALYSQKLT DLRDKRDRVV LEAIREHVRE LEIAESRVMT YANETSMRMQ AASEVGDLRR 840
  841 ISNSVCKLID NQLSALTQLG VIPNDYNDTV QKQEELRAFR DAVQHKLKEP YDAFVIRFRE 900
  901 LMENRLANRD EVVYHNEAIQ AKYCRLMNLC EDRNKLLKSA HGCYKTYETA VLPILNQLES 960
  961 EYHSPTVTDW CAGCTSSIDA DRAAYVADLL SKHMDYKERF GKGCTYALRN GDFLLRYIRR1020
 1021 STVNQSERKR HETKIADMKN NIRERQSNIL ELWMQKKLLL EGCQSFIFIE ASAKELLEFM1080
 1081 KGEGNRKLKH FEKKGRREST DDDDEFAKFK SEVKQKKTDI QTFLMLSTNE TMSRGVHGDE1140
 1141 IDRCIEQVKD EFSRFSRRVG DCEVVLRGEN GSTQSSKDEF SLDRHSDTAI FNEKKINERR1200
 1201 EENRKMLEPM RELIQSERDY IKDLERCVNI YVKEFDQAAK NGTIPTLNPL KYEIFGNIEK1260
 1261 IFKFHNDKLL HELIKYENQP EAVGASFIVW IDLLNELYTE YCVNKEQKNH VIATPDAVSF1320
 1321 FTGIRERHGL EINNEIASLL IKPVQRITRY RLLIEQLMRS CTDKTNDLKE AYEVVCSVPR1380
 1381 KVNDLIHYNC LDLKDFKVDE LGPFVTQDTL TFWEPRAYFK GRGKERQVFL FDISIVFAKR1440
 1441 IEVSPKNIKY VIKGKPLPLS EVSIVEHVEG DTCRFGLRVG TVSSNDNRID LKANNHHTKV1500
 1501 KWVQKIRDLT AGMLPLGLGV SEAYSVGTLS TARSVSVRSG ASTSSGGENR QSQDVESLLR1560
 1561 HRYSVHSCDS EQSSEVWIVT ADFDGQVEGH LTVHKGDRVE IVEDQATDCA EYVQVVLCDQ1620
 1621 PTKHGLVPAS IIAPPESGSV PDRPDDSNAS GSTVSKRKSL RRIFANSSKE RAAAANSSSS1680
 1681 NNNSPATRQS TSTSSPVTAN GHTTESSTSA PIGVLSSGEP TSSNSIPSSS TPTHTVPSSV1740
 1741 PATVIPIVVA EDEKAEDCLP PPMENITINN SIDEKDMNED SVAASDAVEP EVALPAKVEK1800
 1801 TPEETARFKR SYVLMELVET EQDYVKDLTS VVEGYIGNLN KMDLPADLVG KDKIIFANIV1860
 1861 NILEFHKTNF LKEIEKCSEN YEAAGAAFVK YERRLHTLYV TYCQNKPKSD YLLAQDDFEA1920
 1921 FFADTKAKLG HKVALCDLLI KPVQRIMKYQ LLLKDILKFT ERAKDKTDTL KKALQVMHVV1980
 1981 PKACDDMMQV GRLQNFDKSL SAQGKLIHQG TLQISESIAG NVQKPKDRRI FLFEQSAIIA2040
 2041 DHIPPKKEFG NPTYIFKSQF MVNKMVFEPN VPDDPLRFVI KSSDPTQPTS FIANAQSQEE2100
 2101 KDEWNRKMSE LLDQQKRLLA ALVDPRRYND MSSGMGDLSL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: unc-73

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: