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The process whereby phagocytes engulf external particulate material. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte. The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte. The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. The infolding of a membrane, resulting in formation of a vesicle.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: engulfment of apoptotic cell
Acc: GO:0043652
Aspect: Biological Process
Desc: The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
Synonyms:
  • engulfment of apoptotic cell corpse
  • engulfment of cell corpse
Proteins in PDR annotated with:
   This term: 31 [Search]
   Term or descendants: 31 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043652 - engulfment of apoptotic cell (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle