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Protein Overview: hlh-14

General Information:
Name(s) found: hlh-14 / CE36629 [WormBase]
Description(s) found:
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  • WBGene00001958 locus:hlh-14 status:Partially_confirmed UniProt:Q09961 protein_id:CCD65023.1 [WormBase]
  • gi|71982463|ref|NP_495131.2| Helix Loop Helix family member (hlh-14) [Caenorhabditis elegans] [NCBI NR]
  • gi|47270776|gb|AAA68375.2| Helix loop helix protein 14 [Caenorhabditis elegans] [NCBI NR]
  • Helix loop helix protein 14 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE36629 WBGene00001958 locus:hlh-14 helix-loop-helix transcription factor status:Predicted TR:Q09961 protein_id:AAA68375.2 [wormpep150.fasta]
  • 36629 WBGene00001958 locus:hlh-14 helix-loop-helix transcription factor status:Predicted TR:Q09961 protein_id:AAA68375.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CE36629 WBGene00001958 locus:hlh-14 helix-loop-helix transcription factor status:Partially_confirmed UniProt:Q09961_CAEEL protein_id:AAA68375.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE36629 WBGene00001958 locus:hlh-14 helix-loop-helix transcription factor status:Partially_confirmed UniProt:Q09961_CAEEL protein_id:AAA68375.2| [wormORF-contam.fasta]
  • Helix Loop Helix family member (hlh-14) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE36629 WBGene00001958 locus:hlh-14 helix-loop-helix transcription factor status:Partially_confirmed UniProt:Q09961 protein_id:AAA68375.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE36629 WBGene00001958 locus:hlh-14 helix-loop-helix transcription factor status:Partially_confirmed UniProt:Q09961 protein_id:CCD65023.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE36629 WBGene00001958 locus:hlh-14 status:Partially_confirmed UniProt:Q09961 protein_id:CCD65023.1 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 246 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    Biological Process: tail morphogenesis [IMPLink to PubMed article]
    locomotion [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    body morphogenesis [IMPLink to PubMed article]
    regulation of asymmetric cell division [IMPLink to PubMed article]
    regulation of neuron differentiation [IGILink to PubMed article][IMPLink to PubMed article]
    regulation of transcription [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [ISSLink to PubMed article]
    neuron migration [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    neuroblast fate specification [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: DNA binding [ISSLink to PubMed article]
    protein heterodimerization activity [ISSLink to PubMed article]
    transcription regulator activity [IEALink to PubMed article]
    specific RNA polymerase II transcription factor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMLESLIVIF LNSHSCKIFQ ICTSSQSFDL ELFNSSLYNL VPIRFVPIST LLVPPIRLSR  60
   61 PAFPLTISLI HSVHPHSLLA TTVFPLSFYF PAQQKKEAMA KKNQVARNER ERKRVHQVNH 120
  121 GFDVLRNRLQ PKNHTKKWSK ADTLREAVKY IQQLQVLLNQ DPQQPSVSSS TPDYTMNNSN 180
  181 NFNNYAVKEE FSMYLPQNYC PQNQMSVPHG DVSHNFNSPT SSVSSSSYSP TQMCYPPVSY 240
  241 SNYPHH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] deduced N/A No confident structure predictions are available.
    2 View Details [102..246] PSI-BLAST 13.221849 Solution Structure of Max B-HLH-LZ

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.47866819971988 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.04191582741352 bayes_pls_golite062009
  • DNA binding
    		•  1.881116513908 bayes_pls_golite062009
  • transcription factor activity
    		•  1.75305749487981 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.70236865157557 bayes_pls_golite062009
  • protein binding
    		•  0.880820411513 bayes_pls_golite062009
  • transcription activator activity
    		•  0.314165294474 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.52

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle