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The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. The process whereby the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast. The process whereby a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts. The process whereby a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: neuroblast fate specification
Acc: GO:0014018
Aspect: Biological Process
Desc: The process whereby a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0014018 - neuroblast fate specification (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle