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Protein Overview: ATG27

General Information:
Name(s) found: ATG27 / YJL178C [SGD]
Description(s) found:
Found 22 descriptions.
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  • Type I membrane protein involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; may be involved in membrane delivery to the phagophore assembly site [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 271 amino acids

    Gene Ontology:
    Cellular Component: pre-autophagosomal structure [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    membrane [IDALink to PubMed article][ISSLink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    Biological Process: vesicle organization [IMPLink to PubMed article]
    autophagy [IMPLink to PubMed article]
    Molecular Function: protein kinase regulator activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSKTWICGF ISIITVVQAL SCEKHDVLKK YQVGKFSSLT STERDTPPST TIEKWWINVC  60
   61 EEHNVEPPEE CKKNDMLCGL TDVILPGKDA ITTQIIDFDK NIGFNVEETE SALTLTLKGA 120
  121 TWGANSFDAK LEFQCNDNMK QDELTSHTWA DKSIQLTLKG PSGCLKSKDD DKKNGDGDNG 180
  181 KDGDSEGKKP AKKAGGTSWF TWLFLYALLF TLIYLMVVSF LNTRGGSFQD FRAEFIQRST 240
  241 QFLTSLPEFC KEVVSRILGR STAQRGGYSA V

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ASC1 AST2 ATG27 LCB3 NAT3 RKI1 RPL11A RPL11B RPL12B, RPL12A RPL19B, RPL19A RPL1A, RPL1B RPL20B RPL21A RPL21B RPL22A RPL22B RPL23B, RPL23A RPL24A RPL24B RPL26A RPL27B RPL28 RPL29 RPL2A, RPL2B RPL33B RPL34A RPL35A, RPL35B RPL36A RPL38 RPL39 RPL40B, RPL40A RPL41A, RPL41B RPL42B, RPL42A RPL43B, RPL43A RPL6A RPL8A RPL9A RPL9B RPS0A RPS10A RPS10B RPS12 RPS13 RPS14B RPS16B, RPS16A RPS17A RPS17B RPS18B, RPS18A RPS1B RPS21B RPS22A RPS23B, RPS23A RPS24A, RPS24B RPS25A RPS25B RPS26B RPS27A RPS27B RPS30B, RPS30A RPS31 RPS6A, RPS6B RPS7B RPS8B, RPS8A SOP4 TEM1 TOS4 VRP1 YGR117C YPL199C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ATG27 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] MSA 1.010968 View MSA. No confident structure predictions are available.
    2 View Details [109..194] deduced N/A Confident ab initio structure predictions are available.
    3 View Details [195..271] MSA 2.010985 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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