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Protein Overview: MGL_ARATH

General Information:
Name(s) found: MGL_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|6633821|gb|AAF19680.1|AC009519_14 F1N19.23 [Arabidopsis thaliana] [NCBI NR]
  • gi|30387533|gb|AAP31932.1| At1g64660 [Arabidopsis thaliana] [NCBI NR]
  • pir||G96669 protein F1N19.23 [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|16226491|gb|AAL16181.1|AF428413_1 At1g64660/F1N19_22 [Arabidopsis thaliana] [NCBI NR]
  • gi|15450932|gb|AAK96737.1| similar to O-succinylhomoserine sulfhydrylase [Arabidopsis thaliana] [NCBI NR]
  • gi|15217709|ref|NP_176647.1| ATMGL (ARABIDOPSIS THALIANA METHIONINE GAMMA-LYASE); catalytic/ methionine gamma-lyase [Arabidopsis thaliana] [NCBI NR]
  • gi|110740851|dbj|BAE98522.1| similar to O-succinylhomoserine sulfhydrylase [Arabidopsis thaliana] [NCBI NR]
  • Methionine gamma-lyase OS=Arabidopsis thaliana GN=MGL PE=1 SV=1 [Swiss-Prot]
  • (Q9SGU9) F1N19.23 (AT1G64660/F1N19_22) (Similar to O-succinylhomoserine sulfhydrylase) (At1g64660) [athaliana3702.FASTAC.txt]
  • At1g64660 [Arabidopsis thaliana]gi|16226491|gb|AAL16181.1| At1g64660/F1N19_22 [Arabidopsis thaliana]gi|15450932|gb|AAK96737.1| similar to O-succinylhomoserine sulfhydrylase [Arabidopsis thaliana]gi|6633821|gb|AAF19680.1| F1N19.23 [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Cys/Met metabolism pyridoxal-phosphate-dependent enzyme family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATMGL | ATMGL; catalytic/ methionine gamma-lyase | chr1:24032640-24034200 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • similar to O-succinylhomoserine sulfhydrylase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • F1N19.23 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • catalytic [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At1g64660 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At1g64660/F1N19_22 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATMGL, MGL | methionine gamma-lyase | chr1:24028977-24030537 FORWARD LENGTH=441 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 441 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDA]
    Biological Process: cellular amino acid metabolic process [ISS]
    methionine catabolic process via 2-oxobutanoate [TAS]
    Molecular Function: methionine gamma-lyase activity [IDA]
    catalytic activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHFLETQEP LVFSGKKRND RDDEDGDALV AKKSALAVCD ADPAAAIANI RHEFGEHGGV  60
   61 NMSIEASATF TVMEPDTMRR MFTGELGPDN DFYVYSRHFN PTVLNLSRQM AALEGTQAAY 120
  121 CTSSGMSAIS SVMLQLCSSG GHVVAASTLY GGTHALLSHF LPRTCNITTS FVDITDHGAV 180
  181 ANAIVEGRTQ VLYFESVANP TLTVADIPEL SRMAHEKGVT VVVDNTFAPM VLSPAKLGAD 240
  241 VVVHSISKFI SGGADIIAGA VCGSENLVKE MMDLRGGSLM LLGPTMNAKV AFELSERIPH 300
  301 LGLRMREHSH RAQVYAERMR DLGMKVIYPG LETHPQHKLF KGMVNRDYGY GGLLSIDMET 360
  361 EEKANKLMAY LQNATQFGFM AVSLGYYETL MSCSGSSTSS ELDPSQKEAA GISPGLVRMS 420
  421 VGYVGTLEQK WTQFEKAFLR M

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..441] PSI-BLAST 82.69897 Crystal structure of Citrobacter Freundii L-methionine-lyase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  2.82824364293374 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  2.82824364293374 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  1.87460342369605 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.67701710033155 bayes_pls_golite062009
  • DNA binding
    		•  1.4774443071095 bayes_pls_golite062009
  • transferase activity
    		•  1.44093490824786 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.39741122443159 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • transcription factor activity
    		•  1.15775909410582 bayes_pls_golite062009
  • binding
    		•  1.09053123792737 bayes_pls_golite062009
  • O-phospho-L-serine:2-oxoglutarate aminotransferase activity
    		•  0.994935084630764 bayes_pls_golite062009
  • carbon-sulfur lyase activity
    		•  0.698312655247044 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.6849039330512 bayes_pls_golite062009
  • vitamin binding
    		•  0.66463470119531 bayes_pls_golite062009
  • cystathionine gamma-lyase activity
    		•  0.505859361763689 bayes_pls_golite062009
  • alanine-glyoxylate transaminase activity
    		•  0.48682493494502 bayes_pls_golite062009
  • O-acyltransferase activity
    		•  0.452440867878365 bayes_pls_golite062009
  • cysteine synthase activity
    		•  0.417849187928985 bayes_pls_golite062009
  • structural molecule activity
    		•  0.347975812448725 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  0.271623203801431 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • adenosylmethionine-8-amino-7-oxononanoate transaminase activity
    		•  0.0669652799570574 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle