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Catalysis of the elimination of H2S or substituted H2S. Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate. Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: methionine gamma-lyase activity
Acc: GO:0018826
Aspect: Molecular Function
Desc: Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate.
Synonyms:
  • methionine lyase activity
  • L-methionine methanethiol-lyase (deaminating; 2-oxobutanoate-forming)
  • methioninase activity
  • L-methionine methanethiol-lyase (deaminating)
  • methionine dethiomethylase activity
  • L-methioninase activity
  • L-methionine gamma-lyase activity
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0018826 - methionine gamma-lyase activity (interactive image map)

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