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Protein Overview: AB4C_ARATH

General Information:
Name(s) found: AB4C_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|90103510|sp|Q7DM58.2|AB4C_ARATH RecName: Full=ABC transporter C family member 4; Short=ABC transporter ABCC.4; Short=AtABCC4; AltName: Full=Multidrug resistance-associated protein 4; AltName: Full=Glutathione S-conjugate-transporting ATPase 4; AltName: [NCBI NR]
  • gi|7716583|gb|AAF68441.1|AF243509_1 MRP4 [Arabidopsis thaliana] [NCBI NR]
  • gi|3738292|gb|AAC63634.1| glutathione-conjugate transporter AtMRP4 [Arabidopsis thaliana] [NCBI NR]
  • gi|2959767|emb|CAA05625.1| AtMRP4 [Arabidopsis thaliana] [NCBI NR]
  • pir||F84919 glutathione-conjugate transporter AtMRP4 [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|15227133|ref|NP_182301.1| ATMRP4 (ARABIDOPSIS THALIANA MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 4); ATPase, coupled to transmembrane movement of substances / folic acid transporter [Arabidopsis thaliana] [NCBI NR]
  • Multidrug resistance-associated protein 4 OS=Arabidopsis thaliana GN=MRP4 PE=1 SV=2 [Swiss-Prot]
  • ABC transporter C family member 4 OS=Arabidopsis thaliana GN=ABCC4 PE=2 SV=2 [Swiss-Prot]
  • (O24525) ATMRP4 (MRP-like ABC transporter) [athaliana3702.FASTAC.txt]
  • AtMRP4 [Arabidopsis thaliana]gi|3738292|gb|AAC63634.1| glutathione-conjugate transporter AtMRP4 [Arabidopsis thaliana]gi|7716583|gb|AAF68441.1| MRP4 [Arabidopsis thaliana]gi|15227133|ref|NP_182301.1| glutathione-conjugate transporter (MRP4) [Arabidopsi [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Glutathione-conjugate transporter (MRP4) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: EST3, ATMRP4 | ATMRP4 (Arabidopsis thaliana multidrug resistance-associated protein 4) | chr2:19582014-19587453 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • ATMRP4 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • AtMRP4 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • glutathione-conjugate transporter AtMRP4 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • MRP4 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Multidrug resistance-associated protein 4 (Glutathione S-conjugate-transporting ATPase 4) (ATP-energized glutathione S-conjugate pump 4) [nr-271106-contam.fasta]
  • | Symbols: ATMRP4, EST3, MRP4, ABCC4 | multidrug resistance-associated protein 4 | chr2:19574944-19580383 FORWARD LENGTH=1516 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • ABC transporter C family member 4 OS=Arabidopsis thaliana GN=ABCC4 PE=1 SV=2 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 1516 amino acids

    Gene Ontology:
    Cellular Component: plant-type vacuole [IDA]
    vacuolar membrane [IDA]
    vacuole [IDA]
    plasma membrane [IDA][TAS]
    Biological Process: drug transmembrane transport [ISS]
    response to wounding [IEP]
    stomatal movement [IMP]
    response to nematode [IEP]
    response to water deprivation [IMP]
    Molecular Function: ATPase activity, coupled to transmembrane movement of substances [ISS]
    folic acid transporter activity [IGI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWLLSSSPWL SELSCSYSAV VEHTSSVPVP IQWLRFVLLS PCPQRALFSA VDFIFLLCFA  60
   61 LHKLFSSPSS SSEINGHAEI RKPLIGIRGR TPTRTTAWFK TTVAVTVLLS FCSVVLCVLA 120
  121 FTGKRRTQRP WNLIDPLFWL IHAVTHLVIA VLVLHQKRFA ALNHPLSLRI YWISSFVLTS 180
  181 LFAVTGIFHF LSDAATSLRA EDVASFFSFP LTAFLLIASV RGITGLVTAE TNSPTKPSDA 240
  241 VSVEKSDNVS LYASASVFSK TFWLWMNPLL SKGYKSPLTL EQVPTLSPEH KAERLALLFE 300
  301 SSWPKPSENS SHPIRTTLLR CFWKEILFTA ILAIVRLGVM YVGPVLIQSF VDFTSGKRSS 360
  361 PWQGYYLVLI LLVAKFVEVL TTHQFNFDSQ KLGMLIRSTL ITALYKKGLK LTGSARQNHG 420
  421 VGQIVNYMAV DAQQLSDMML QLHAIWLMPL QVTVALVLLY GSLGASVITA VIGLTGVFVF 480
  481 ILLGTQRNNG YQFSLMGNRD SRMKATNEML NYMRVIKFQA WENHFNKRIL KFRDMEFGWL 540
  541 SKFLYSIAGN IIVLWSTPVL ISALTFATAL ALGVKLDAGT VFTTTTIFKI LQEPIRTFPQ 600
  601 SMISLSQAMI SLGRLDSYMM SKELSEDAVE RALGCDGNTA VEVRDGSFSW DDEDNEPALS 660
  661 DINFKVKKGE LTAIVGTVGS GKSSLLASVL GEMHRISGQV RVCGSTGYVA QTSWIENGTV 720
  721 QDNILFGLPM VREKYNKVLN VCSLEKDLQM MEFGDKTEIG ERGINLSGGQ KQRIQLARAV 780
  781 YQECDVYLLD DVFSAVDAHT GSDIFKKCVR GALKGKTVLL VTHQVDFLHN VDCILVMRDG 840
  841 KIVESGKYDE LVSSGLDFGE LVAAHETSME LVEAGADSAA VATSPRTPTS PHASSPRTSM 900
  901 ESPHLSDLND EHIKSFLGSH IVEDGSKLIK EEERETGQVS LGVYKQYCTE AYGWWGIVLV 960
  961 LFFSLTWQGS LMASDYWLAY ETSAKNAISF DASVFILGYV IIALVSIVLV SIRSYYVTHL1020
 1021 GLKTAQIFFR QILNSILHAP MSFFDTTPSG RILSRASTDQ TNVDILIPFM LGLVVSMYTT1080
 1081 LLSIFIVTCQ YAWPTAFFVI PLGWLNIWYR NYYLASSREL TRMDSITKAP IIHHFSESIA1140
 1141 GVMTIRSFRK QELFRQENVK RVNDNLRMDF HNNGSNEWLG FRLELVGSWV LCISALFMVL1200
 1201 LPSNVIRPEN VGLSLSYGLS LNSVLFFAIY MSCFVENKMV SVERIKQFTD IPSESEWERK1260
 1261 ETLPPSNWPF HGNVHLEDLK VRYRPNTPLV LKGITLDIKG GEKVGVVGRT GSGKSTLIQV1320
 1321 LFRLVEPSGG KIIIDGIDIS TLGLHDLRSR FGIIPQEPVL FEGTVRSNID PTEQYSDEEI1380
 1381 WKSLERCQLK DVVATKPEKL DSLVVDNGEN WSVGQRQLLC LGRVMLKRSR LLFLDEATAS1440
 1441 VDSQTDAVIQ KIIREDFASC TIISIAHRIP TVMDGDRVLV IDAGKAKEFD SPARLLERPS1500
 1501 LFAALVQEYA LRSAGI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..232] deduced N/A No confident structure predictions are available.
    2 View Details [233..356] MSA 1.455989 View MSA. No confident structure predictions are available.
    3 View Details [357..416] deduced N/A No confident structure predictions are available.
    4 View Details [417..639] deduced N/A No confident structure predictions are available.
    5 View Details [640..921] PSI-BLAST 67.0 No description for 2cbzA was found.
    6 View Details [922..1516] PSI-BLAST 152.0 No description for 3b5xA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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