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Protein Overview: CAMK2_ARATH

General Information:
Name(s) found: CAMK2_ARATH [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • CDPK-related kinase 2 OS=Arabidopsis thaliana GN=CRK2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 599 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA]
    Biological Process: protein amino acid phosphorylation [IEA]
    Molecular Function: ATP binding [IEA]
    calcium-dependent protein serine/threonine phosphatase activity [ISS]
    calcium ion binding [ISS]
    protein kinase activity [IEA]
    protein serine/threonine kinase activity [IEA]
    kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGCTSKPSS SVKPNPYAPK DAVLQNDDST PAHPGKSPVR SSPAVKASPF FPFYTPSPAR  60
   61 HRRNKSRDGG GGESKSVTST PLRQLARAFH PPSPARHIRD VLRRRKEKKE AALPAARQQK 120
  121 EEEEREEVGL DKRFGFSKEL QSRIELGEEI GRGHFGYTCS AKFKKGELKD QEVAVKVIPK 180
  181 SKMTSAISIE DVRREVKILR ALSGHQNLVQ FYDAFEDNAN VYIVMELCGG GELLDRILAR 240
  241 GGKYSEDDAK AVLIQILNVV AFCHLQGVVH RDLKPENFLY TSKEENSMLK VIDFGLSDFV 300
  301 RPDERLNDIV GSAYYVAPEV LHRSYTTEAD VWSIGVIAYI LLCGSRPFWA RTESGIFRAV 360
  361 LKADPSFDEP PWPSLSFEAK DFVKRLLYKD PRKRMTASQA LMHPWIAGYK KIDIPFDILI 420
  421 FKQIKAYLRS SSLRKAALMA LSKTLTTDEL LYLKAQFAHL APNKNGLITL DSIRLALATN 480
  481 ATEAMKESRI PDFLALLNGL QYKGMDFEEF CAASISVHQH ESLDCWEQSI RHAYELFEMN 540
  541 GNRVIVIEEL ASELGVGSSI PVHTILNDWI RHTDGKLSFL GFVKLLHGVS TRQSLAKTR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..415] PSI-BLAST 61.0 Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)
    2 View Details [416..484] FFAS03 2.1 Regulatory apparatus of Calcium Dependent protein kinase from Arabidopsis thaliana
    3 View Details [485..599] PSI-BLAST 13.30103 Calcineurin regulatory subunit (B-chain)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.04467222534257 bayes_pls_golite062009
  • kinase activity
    		•  4.85903980916957 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.63692708178478 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • calmodulin-dependent protein kinase activity
    		•  4.31938467136214 bayes_pls_golite062009
  • transferase activity
    		•  3.26787750561728 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • tubulin binding
    		•  2.18641675163967 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.12615078788254 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • microtubule binding
    		•  1.88110801192607 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  1.3898059094397 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.38496328649031 bayes_pls_golite062009
  • molecular adaptor activity
    		•  1.33740973673697 bayes_pls_golite062009
  • actin binding
    		•  1.33479685165255 bayes_pls_golite062009
  • gamma-tubulin binding
    		•  1.28511591054866 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  1.27291233344322 bayes_pls_golite062009
  • SH3/SH2 adaptor activity
    		•  1.2323381312171 bayes_pls_golite062009
  • protein binding
    		•  1.22565748038754 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.10597058961079 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.06086848160606 bayes_pls_golite062009
  • DNA binding
    		•  0.956433441855102 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.83823250804321 bayes_pls_golite062009
  • transcription factor activity
    		•  0.790106588313006 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.612883428421652 bayes_pls_golite062009
  • transporter activity
    		•  0.553953601841147 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.499492353295369 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.37676337669549 bayes_pls_golite062009
  • protein complex binding
    		•  0.343240719858581 bayes_pls_golite062009
  • signal transducer activity
    		•  0.270054246024761 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.270054246024761 bayes_pls_golite062009
  • actin filament binding
    		•  0.2403700250846 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.08504542461349 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.0611721261859464 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.0556163711947139 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.00652065412910241 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  3.49668552859347 bayes_pls_golite062009
  • motor activity
    		•  3.25814691068414 bayes_pls_golite062009
  • binding
    		•  3.17556402087346 bayes_pls_golite062009
  • tubulin binding
    		•  2.51210014078446 bayes_pls_golite062009
  • actin binding
    		•  2.38676888633305 bayes_pls_golite062009
  • microtubule binding
    		•  2.17136406283012 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.77004149096367 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.43263098461462 bayes_pls_golite062009
  • calcium ion binding
    		•  1.40919295397643 bayes_pls_golite062009
  • ion binding
    		•  1.36376383271837 bayes_pls_golite062009
  • metal ion binding
    		•  1.34827363853601 bayes_pls_golite062009
  • cation binding
    		•  1.34827363853601 bayes_pls_golite062009
  • DNA binding
    		•  1.34235138376625 bayes_pls_golite062009
  • protein binding
    		•  1.16246005294206 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.05536109719637 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.02622810676526 bayes_pls_golite062009
  • kinase activity
    		•  1.01041521285233 bayes_pls_golite062009
  • structural constituent of muscle
    		•  0.99845401805886 bayes_pls_golite062009
  • actin filament binding
    		•  0.836375875773328 bayes_pls_golite062009
  • structural molecule activity
    		•  0.800850121197479 bayes_pls_golite062009
  • G-protein beta/gamma-subunit binding
    		•  0.77824189826064 bayes_pls_golite062009
  • transporter activity
    		•  0.594904129738596 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.346694954512987 bayes_pls_golite062009
  • transferase activity
    		•  0.297929823471296 bayes_pls_golite062009
  • myosin binding
    		•  0.125186564742711 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.116648335890738 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.0834423172982799 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.0489908313324834 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle