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Protein Overview: NEK7_ARATH

General Information:
Name(s) found: NEK7_ARATH [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • Serine/threonine-protein kinase Nek7 OS=Arabidopsis thaliana GN=NEK7 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 571 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: protein amino acid phosphorylation [IEA]
    Molecular Function: ATP binding [IEA]
    protein tyrosine kinase activity [IEA]
    protein kinase activity [IEA]
    protein serine/threonine kinase activity [IEA]
    kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQMEANDCQE EHKFTLDNYH VVEQVRRGKS SSDFVVLHDI EDKKYAMKKI CLAKHTDKLK  60
   61 QTALQEMKLL SSLKNPYIVH YEDSWIDNDN NACIFTAYYE GGNMANAIKK ARGKLFPEER 120
  121 IFKWLAQLLL AVNYLHSNRV VHMDLTCSNI FLPKDDHVQL GNYGLAKLIN PEKPVSMVSG 180
  181 ISNSMCPEVL EDQPYGYKSD IWSLGCCMYE ITAHQPAFKA PDMAGLINKI NRSLMSPLPI 240
  241 VYSSTLKQMI KLMLRKKPEY RPTACELLRN PSLQPYLLQC QNLSPIYLPV FPIKPVNSPK 300
  301 DKARRNSLPG KFGKERVSRE KSEVSRSLEN LYPFWTNTET GSSSSSQPAS STNGAEDKLE 360
  361 TKRIDPSCDT LKISEFTSQK SDESLIDPDI AVYSTETPAE ENALPKETEN IFSEESQLRD 420
  421 VDVGVVSAQE VACSPPRAIE EAETQEALPK PKEQITVPIS SVAHSSTEVA AAKDHLSGSL 480
  481 EGDKAKMVKL TASEMSSVLS KLTKLGPPQS KERADALECL LEKCAGLVKQ EKYEELAGLL 540
  541 TPFGEDGVSA RDTAIWFAKT LLSSDKLNQG T

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..328] PSI-BLAST 76.69897 No description for 2jdoA was found.
    2 View Details [329..483] deduced N/A No confident structure predictions are available.
    3 View Details [484..571] PSI-BLAST 11.154902 No description for 2qlvA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • calmodulin-dependent protein kinase activity
    		•  4.31938467136214 bayes_pls_golite062009
  • transferase activity
    		•  3.97138602499442 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  1.3898059094397 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.38496328649031 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  1.27291233344322 bayes_pls_golite062009
  • protein binding
    		•  1.22565748038754 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.684204466593894 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.499492353295369 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.35402045013148 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.26024936404169 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  0.196560862858137 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle