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Protein Overview: SYMC_ARATH

General Information:
Name(s) found: SYMC_ARATH [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • Methionine--tRNA ligase, cytoplasmic OS=Arabidopsis thaliana GN=At4g13780 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 797 amino acids

    Gene Ontology:
    Cellular Component: cytosol [TAS]
    Biological Process: methionyl-tRNA aminoacylation [ISS]
    response to cadmium ion [IEP]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    aminoacyl-tRNA ligase activity [IEA]
    methionine-tRNA ligase activity [IEA][ISS]
    tRNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDDGKSSPK LPIPGKRNIL ITSALPYVNN VPHLGNIIGC VLSADVYARY CRLRGYNAIY  60
   61 ICGTDEYGTA TETKALEENC TPKEICDKYH AIHKEVYDWF GISFDKFGRT STPEQTEVCQ 120
  121 AIFNKLWDNK WLSENTMQQL YCDTCKKFLA DRLVEGSCPF EGCNYDSARG DQCEKCGKLL 180
  181 NPTELKDPKC KVCQNTPRIR DTDHLFIELP LLKDRLEAYI KKTSVTGSWS QNAIQTTNAW 240
  241 LRDGLRQRCI TRDLKWGVPV PHEKYKDKVF YVWFDAPIGY VSITSCYTSE WEKWWKNPEN 300
  301 VELYQFMGKD NVPFHTVMFP STQLGTEENW TLMKTISVTE YLNYEDGKFS KSKGVGVFGN 360
  361 DVKDTNIPVE VWRYYLLTNR PEVSDTSFSW TDLQAKLNGE LLSNLGNFVN RVLSFIAKPD 420
  421 NAGYGSVIPD AHDAESHSLT KSLAEKVEKF VAEYVEAMEK VKLKQGLKTA MLISSEGNYY 480
  481 LQASQFWKLY KEDKPLCAVV IRTAAGLVHL LAQLLEPFMP SFSCEVFKQL NLPPQFSLSD 540
  541 ERGEVLLASR PWDILPPSHR IGTPQPLFKE LENDEVARYR EKFAGSQSDR RARDEAANLA 600
  601 DQLNKTKLSD AKKQKASSKG GGKPKPQPAA DREITMARLD IRVGKIVKAE KHPKADALYV 660
  661 EEIDVGGGEI RTVVSGLVKY IPLEEMQNRM VCVLCNLKPA KMRDIVSQAM VLAASSSDGS 720
  721 KVELVEPPKT ANIGERVTFP GFEGEPDDVL NPKKKVWETL LVDLNTKENL VACYKDVPFT 780
  781 TSAGVCKVSS ISNGTIR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..737] PSI-BLAST 141.0 Methionyl-tRNA synthetase from Pyrococcus abyssi
    2 View Details [738..797] PSI-BLAST 38.09691 EMAP II

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  5.54691369460949 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  4.64665624411373 bayes_pls_golite062009
  • isoleucine-tRNA ligase activity
    		•  3.76808520367507 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  3.33137779158831 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.50161401062914 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.06535308346284 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • binding
    		•  0.683583881070171 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.449504767632354 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle