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Protein Overview: MSI4_ARATH

General Information:
Name(s) found: MSI4_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|61661316|gb|AAX51264.1| FVE [Arabidopsis thaliana] [NCBI NR]
  • gi|30680701|ref|NP_565456.2| FVE; metal ion binding [Arabidopsis thaliana] [NCBI NR]
  • gi|30268750|gb|AAP29475.1|AF498102_1 MSI4 [Arabidopsis thaliana] [NCBI NR]
  • gi|30268748|gb|AAP29474.1|AF498101_1 MSI4 [Arabidopsis thaliana] [NCBI NR]
  • pir||G84577 probable WD-40 repeat protein, MSI4 [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|22096353|sp|O22607.3|MSI4_ARATH RecName: Full=WD-40 repeat-containing protein MSI4; AltName: Full=Altered cold-responsive gene 1 protein [NCBI NR]
  • gi|20148237|gb|AAM10009.1| putative WD-40 repeat protein, MSI4 [Arabidopsis thaliana] [NCBI NR]
  • gi|16648859|gb|AAL24281.1| putative WD-40 repeat protein, MSI4 [Arabidopsis thaliana] [NCBI NR]
  • gi|16323103|gb|AAL15286.1| At2g19520/F3P11.12 [Arabidopsis thaliana] [NCBI NR]
  • WD-40 repeat-containing protein MSI4 OS=Arabidopsis thaliana GN=MSI4 PE=1 SV=3 [Swiss-Prot]
  • (O22607) WD-40 repeat protein MSI4 [athaliana3702.FASTAC.txt]
  • putative WD-40 repeat protein, MSI4 [Arabidopsis thaliana]gi|16648859|gb|AAL24281.1| putative WD-40 repeat protein, MSI4 [Arabidopsis thaliana]gi|16323103|gb|AAL15286.1| At2g19520/F3P11.12 [Arabidopsis thaliana]gi|25411913|pir||G84577 probable WD-40 re [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 WD-40 repeat protein MSI4 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ACG1, MSI4, NFC4, NFC04, ATMSI4, FVE | FVE | chr2:8463088-8466317 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • WD-40 repeat protein MSI4 (Altered cold-responsive gene 1 protein) [nr-271106-contam.fasta]
  • MSI4 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • FVE (FVE) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative WD-40 repeat protein, MSI4 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At2g19520/F3P11.12 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • FVE [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: FVE, ACG1, MSI4, NFC4, NFC04, ATMSI4 | Transducin family protein / WD-40 repeat family protein | chr2:8456006-8459235 FORWARD LENGTH=507 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 507 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    nucleolus [IDA]
    CUL4 RING ubiquitin ligase complex [ISS]
    Biological Process: unidimensional cell growth [IMP]
    flower development [IMP]
    trichome morphogenesis [IMP]
    leaf morphogenesis [IMP]
    Molecular Function: metal ion binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESDEAAAVS PQATTPSGGT GASGPKKRGR KPKTKEDSQT PSSQQQSDVK MKESGKKTQQ  60
   61 SPSVDEKYSQ WKGLVPILYD WLANHNLVWP SLSCRWGPQL EQATYKNRQR LYLSEQTDGS 120
  121 VPNTLVIANC EVVKPRVAAA EHISQFNEEA RSPFVKKYKT IIHPGEVNRI RELPQNSKIV 180
  181 ATHTDSPDVL IWDVETQPNR HAVLGAANSR PDLILTGHQD NAEFALAMCP TEPFVLSGGK 240
  241 DKSVVLWSIQ DHITTIGTDS KSSGSIIKQT GEGTDKNESP TVGPRGVYHG HEDTVEDVAF 300
  301 SPTSAQEFCS VGDDSCLILW DARTGTNPVT KVEKAHDADL HCVDWNPHDD NLILTGSADN 360
  361 TVRLFDRRKL TANGVGSPIY KFEGHKAAVL CVQWSPDKSS VFGSSAEDGL LNIWDYDRVS 420
  421 KKSDRAAKSP AGLFFQHAGH RDKVVDFHWN ASDPWTIVSV SDDCETTGGG GTLQIWRMSD 480
  481 LIYRPEEEVV AELEKFKSHV MTCASKP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..507] PSI-BLAST 46.39794 Actin interacting protein 1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • histone methyltransferase activity (H3-K4 specific)
    		•  4.71992275913384 bayes_pls_golite062009
  • acetyltransferase activity
    		•  3.85374902981345 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.35098520158193 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.31615347567536 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.14917998298348 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.79445416141967 bayes_pls_golite062009
  • snoRNA binding
    		•  2.62514080753887 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.3610959773142 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.30918780727915 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.29049708962212 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  2.18628561734369 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.85632145559025 bayes_pls_golite062009
  • DNA binding
    		•  1.71685536470455 bayes_pls_golite062009
  • dynein binding
    		•  1.62099593211487 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.41752877005447 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  1.35170368882651 bayes_pls_golite062009
  • protein binding
    		•  1.21879977456466 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.19593750149343 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • transcription factor activity
    		•  1.08768505897883 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  1.01962930136588 bayes_pls_golite062009
    		• 0.88172763425403 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.676924760416604 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.625780732991652 bayes_pls_golite062009
  • actin binding
    		•  0.529861581509437 bayes_pls_golite062009
  • transcription factor binding
    		•  0.489473003915035 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.428715007921149 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.426429095658617 bayes_pls_golite062009
  • kinase activity
    		•  0.387572734234845 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30761651528651 bayes_pls_golite062009
  • transporter activity
    		•  0.284701931503833 bayes_pls_golite062009
  • structural molecule activity
    		•  0.254012051644049 bayes_pls_golite062009
  • protein kinase activity
    		•  0.229242350006544 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.226335610368636 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.220747580531792 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.161639372576406 bayes_pls_golite062009
  • chromatin binding
    		•  0.151977098745772 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  0.00335766408304172 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle