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Protein Overview: CNGC6_ARATH

General Information:
Name(s) found: CNGC6_ARATH [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
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  • Probable cyclic nucleotide-gated ion channel 6 OS=Arabidopsis thaliana GN=CNGC6 PE=1 SV=2 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 747 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA]
    Biological Process: response to cadmium ion [IEP]
    Molecular Function: calmodulin binding [IEP][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDTCGPKGV KSQVISGQRE NFVRLDSMDS RYSQSSETGL NKCTLNIQGG PKRFAQGSKA  60
   61 SSGSFKKGFR KGSEGLWSIG RSIGLGVSRA VFPEDLEVSE KKIFDPQDKF LLLCNKLFVA 120
  121 SCILAVSVDP LFLYLPFIND KAKCVGIDRK LAIIVTTIRT VIDSFYLFHM ALRFRTAYVA 180
  181 PSSRVFGRGE LVIDPAQIAK RYLQQYFIID LLSVLPVPQI IVWRFLYTSR GANVLATKQA 240
  241 LRYIVLVQYI PRFLRMYPLS SELKRTAGVF AETAWAGAAY YLLLYMLASH IVGALWYLLA 300
  301 LERNNDCWSK ACHNNQNCTR NFLFCGNQNM KGYAAWDNIK VSYLQLKCPV NVPEDEEPPF 360
  361 DFGIYLRALS SGIVSSKNFV SKYFFCLWWG LQNLSTLGQG LETSTYPGEV IFSITLAIAG 420
  421 LLLFALLIGN MQTYLQSLTI RLEEMRVKRR DSEQWMHHRM LPPELRERVR RYDQYKWLET 480
  481 RGVDEENLVQ NLPKDLRRDI KRHLCLALVR RVPLFENMDE RLLDAICERL KPCLFTEKSY 540
  541 LVREGDPVNE MLFIIRGRLE SVTTDGGRSG FYNRSLLKEG DFCGDELLTW ALDPKSGSNL 600
  601 PSSTRTVKAL TEVEAFALIA DELKFVASQF RRLHSRQVQH TFRFYSQQWR TWAACFMQAA 660
  661 WRRYIKRKKL EQLRKEEEEE EAAAASVIAG GSPYSIRATF LASKFAANAL RSVHKNRTAK 720
  721 STLLLSSTKE LVKFQKPPEP DFSAEDH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] deduced N/A No confident structure predictions are available.
    2 View Details [85..230] FFAS03 1.5 Crystal structure of KvAP-33H1 Fv complex
    3 View Details [231..497] PSI-BLAST 16.221849 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
    4 View Details [498..650] PSI-BLAST 18.221849 Solution structure of the cNMP-binding domain from Arabidopsis thaliana cyclic nucleotide-regulated ion channel
    5 View Details [651..747] PSI-BLAST 29.39794 Catabolite gene activator protein (CAP), C-terminal domain; Catabolite gene activator protein, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • cyclic nucleotide-gated ion channel activity
    		•  9.28636958853471 bayes_pls_golite062009
  • intracellular cyclic nucleotide activated cation channel activity
    		•  9.28636958853471 bayes_pls_golite062009
  • intracellular cGMP activated cation channel activity
    		•  9.19973076787954 bayes_pls_golite062009
  • intracellular ligand-gated ion channel activity
    		•  8.92326348606261 bayes_pls_golite062009
  • cGMP binding
    		•  7.7575871125398 bayes_pls_golite062009
  • cyclic nucleotide binding
    		•  7.37322432929433 bayes_pls_golite062009
  • GMP binding
    		•  5.49455172024846 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  2.24160712920592 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  2.24160712920592 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.1641765932136 bayes_pls_golite062009
  • ion channel activity
    		•  1.99113461395381 bayes_pls_golite062009
  • gated channel activity
    		•  1.96880619620616 bayes_pls_golite062009
  • channel activity
    		•  1.95481941885364 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  1.95481941885364 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  1.9532743483506 bayes_pls_golite062009
  • cation channel activity
    		•  1.8875306855156 bayes_pls_golite062009
  • binding
    		•  1.03706428234992 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.745476294699195 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.646885146396875 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.582561336941853 bayes_pls_golite062009
  • protein binding
    		•  0.560659365968498 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.489669604147601 bayes_pls_golite062009
  • transporter activity
    		•  0.232363663369302 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.209203009093296 bayes_pls_golite062009
    5
    Term Confidence Notes
  • binding
    		•  2.33495708130358 bayes_pls_golite062009
  • DNA binding
    		•  1.3643232454136 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.27790965988833 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.931016322768698 bayes_pls_golite062009
  • transcription factor activity
    		•  0.880776321779274 bayes_pls_golite062009
  • protein binding
    		•  0.501337284874473 bayes_pls_golite062009
  • transcription activator activity
    		•  0.225529556408477 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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