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Protein Overview: CNGC2_ARATH

General Information:
Name(s) found: CNGC2_ARATH [Swiss-Prot]
Description(s) found:
Found 18 descriptions.
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  • Cyclic nucleotide-gated ion channel 2 OS=Arabidopsis thaliana GN=CNGC2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 726 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    endomembrane system [IEA]
    Biological Process: nitric oxide mediated signal transduction [IMP]
    defense response [TAS]
    plant-type hypersensitive response [IMP]
    Molecular Function: calmodulin binding [TAS]
    calcium channel activity [IMP]
    cation channel activity [ISS]
    inward rectifier potassium channel activity [IGI]
    intracellular cAMP activated cation channel activity [IDA]
    cyclic nucleotide binding [ISS]
    intracellular cyclic nucleotide activated cation channel activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSHPNFIFR WIGLFSDKFR RQTTGIDENS NLQINGGDSS SSGSDETPVL SSVECYACTQ  60
   61 VGVPAFHSTS CDQAHAPEWR ASAGSSLVPI QEGSVPNPAR TRFRRLKGPF GEVLDPRSKR 120
  121 VQRWNRALLL ARGMALAVDP LFFYALSIGR TTGPACLYMD GAFAAVVTVL RTCLDAVHLW 180
  181 HVWLQFRLAY VSRESLVVGC GKLVWDPRAI ASHYARSLTG FWFDVIVILP VPQAVFWLVV 240
  241 PKLIREEKVK LIMTILLLIF LFQFLPKIYH CICLMRRMQK VTGYIFGTIW WGFALNLIAY 300
  301 FIASHVAGGC WYVLAIQRVA SCIRQQCMRT GNCNLSLACK EEVCYQFVSP TSTVGYPCLS 360
  361 GNLTSVVNKP MCLDSNGPFR YGIYRWALPV ISSNSLAVKI LYPIFWGLMT LSTFANDLEP 420
  421 TSNWLEVIFS IVMVLSGLLL FTLLIGNIQV FLHAVMAKKR KMQIRCRDME WWMKRRQLPS 480
  481 RLRQRVRRFE RQRWNALGGE DELELIHDLP PGLRRDIKRY LCFDLINKVP LFRGMDDLIL 540
  541 DNICDRAKPR VFSKDEKIIR EGDPVQRMIF IMRGRVKRIQ SLSKGVLATS TLEPGGYLGD 600
  601 ELLSWCLRRP FLDRLPPSSA TFVCLENIEA FSLGSEDLRY ITDHFRYKFA NERLKRTARY 660
  661 YSSNWRTWAA VNIQMAWRRR RKRTRGENIG GSMSPVSENS IEGNSERRLL QYAAMFMSIR 720
  721 PHDHLE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] MSA 1.173996 View MSA. No confident structure predictions are available.
    2 View Details [110..244] FFAS03 1.62 Crystal structure of KvAP-33H1 Fv complex
    3 View Details [245..476] PSI-BLAST 5.522879 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
    4 View Details [477..661] PSI-BLAST 29.0 No description for 2q0aA was found.
    5 View Details [662..726] PSI-BLAST 28.522879 Catabolite gene activator protein (CAP), C-terminal domain; Catabolite gene activator protein, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  0.835523092977445 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.4843036104266 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.37117756729668 bayes_pls_golite062009
  • DNA binding
    		•  0.3118855114645 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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