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Protein Overview: ncs1

General Information:
Name(s) found: ncs1 / SPAC18B11.04 [Sanger Pombe]
Description(s) found:
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  • gi|929890|emb|CAA90589.1| related to neuronal calcium sensor Ncs1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|37903738|gb|AAP48992.1| neuronal calcium sensor protein-like protein; Ncs1p [Schizosaccharomyces pombe] [NCBI NR]
  • pir||S58303 related to neuronal calcium sensor 1 proteins - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19113791|ref|NP_592879.1| related to neuronal calcium sensor Ncs1 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|1171671|sp|Q09711.2|NCS1_SCHPO RecName: Full=Calcium-binding protein NCS-1 [NCBI NR]
  • related to neuronal calcium sensor Ncs1 [Sanger Pombe]
  • Calcium-binding protein NCS-1 OS=Schizosaccharomyces pombe GN=ncs1 PE=1 SV=2 [Swiss-Prot]
  • RELATED TO NEURONAL CALCIUM SENSOR 1 PROTEINS: Q09711; [pompepVF.fasta]
  • |||related to neuronal calcium sensor 1 proteins [pompepnew.fasta]
  • |ncs1||related to neuronal calcium sensor 1|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • related to neuronal calcium sensor 1 proteins [Schizosaccharomyces pombe]gi|929890|emb|CAA90589.1| SPAC18B11.04 [Schizosaccharomyces pombe]gi|37903738|gb|AAP48992.1| neuronal calcium sensor protein-like protein; Ncs1p [Schizosaccharomyces pombe]gi|2119 [nrdb_11152004_Chlamydomonas]
  • |ncs1||related to neuronal calcium sensor Ncs1|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC18B11.04 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC18B11.04 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Neuronal calcium sensor 1 (NCS-1) [nr-271106-contam.fasta]
  • neuronal calcium sensor protein-like protein; Ncs1p [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Calcium-binding protein NCS-1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ncs1 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 190 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    extrinsic to membrane [IEA]
    plasma membrane [IDALink to PubMed article]
    Biological Process: cAMP-mediated signaling [TASLink to PubMed article]
    cellular calcium ion homeostasis [TASLink to PubMed article]
    regulation of conjugation with cellular fusion [IMPLink to PubMed article]
    Molecular Function: calcium ion binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKSQSKLSQ DQLQDLVRST RFDKKELQQW YKGFFKDCPS GHLNKSEFQK IYKQFFPFGD  60
   61 PSAFAEYVFN VFDADKNGYI DFKEFICALS VTSRGELNDK LIWAFQLYDL DNNGLISYDE 120
  121 MLRIVDAIYK MVGSMVKLPE DEDTPEKRVN KIFNMMDKNK DGQLTLEEFC EGSKRDPTIV 180
  181 SALSLYDGLV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..190] PSI-BLAST 38.30103 Neurocalcin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  7.47426847861728 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  6.37104157544514 bayes_pls_golite062009
  • phosphatase activity
    		•  6.28157965296365 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.17799259119197 bayes_pls_golite062009
  • calcium-dependent protein serine/threonine phosphatase activity
    		•  5.58369939851095 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.11186887221409 bayes_pls_golite062009
  • calcium-dependent protein serine/threonine phosphatase regulator activity
    		•  4.70715233640875 bayes_pls_golite062009
  • calcium ion binding
    		•  3.79609619542776 bayes_pls_golite062009
  • binding
    		•  3.17556402087346 bayes_pls_golite062009
  • cation binding
    		•  2.62077305565026 bayes_pls_golite062009
  • metal ion binding
    		•  2.62077305565026 bayes_pls_golite062009
  • ion binding
    		•  2.61312132078717 bayes_pls_golite062009
  • clathrin binding
    		•  2.36616108128297 bayes_pls_golite062009
  • protein binding
    		•  2.21291432166051 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.9739523190593 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.6550001867465 bayes_pls_golite062009
  • DNA binding
    		•  1.55722307354604 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.53225451586959 bayes_pls_golite062009
  • structural constituent of muscle
    		•  1.30577051923353 bayes_pls_golite062009
  • calcium-dependent protein kinase inhibitor activity
    		•  1.29632226581856 bayes_pls_golite062009
  • actin filament binding
    		•  1.25849450788569 bayes_pls_golite062009
  • actin binding
    		•  1.1967948958876 bayes_pls_golite062009
  • transporter activity
    		•  1.15928534291452 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.11607939838219 bayes_pls_golite062009
  • signal transducer activity
    		•  1.11607939838219 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.945691505472547 bayes_pls_golite062009
  • phosphatase regulator activity
    		•  0.87149881541475 bayes_pls_golite062009
  • motor activity
    		•  0.85125321350375 bayes_pls_golite062009
  • guanylate cyclase regulator activity
    		•  0.84389905735679 bayes_pls_golite062009
  • cyclase regulator activity
    		•  0.84389905735679 bayes_pls_golite062009
  • protein phosphatase regulator activity
    		•  0.822713961141111 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.787740261079819 bayes_pls_golite062009
  • kinase activity
    		•  0.782396352346639 bayes_pls_golite062009
  • calcium channel regulator activity
    		•  0.7164851905066 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.693724160233023 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.666488715029225 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.654002071540024 bayes_pls_golite062009
  • calcium sensitive guanylate cyclase activator activity
    		•  0.630360514213104 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.515693296786409 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.45412801027969 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.246383459363256 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.193201281459889 bayes_pls_golite062009
  • structural molecule activity
    		•  0.048100972187449 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0305250212662123 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle