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View Structure Prediction Details

Protein: ncs1
Organism: Schizosaccharomyces pombe
Length: 190 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ncs1.

Description E-value Query
Range
Subject
Range
gi|73980372 - gi|73980372|ref|XP_852217.1| PREDICTED: similar to hippocalcin-like 1 [Canis familiaris]
185.0 [0..1] [184..137]
gi|109001730 - gi|109001730|ref|XP_001098851.1| PREDICTED: similar to Neuron-specific calcium-binding protein hippo...
184.0 [0..1] [184..216]
gi|114555708 - gi|114555708|ref|XP_001155509.1| PREDICTED: similar to Neuron specific calcium-binding protein P23K ...
184.0 [0..1] [184..152]
gi|76668066 - gi|76668066|ref|XP_609831.2| PREDICTED: similar to Hippocalcin-like protein 4 (HLP4) [Bos taurus]
167.0 [0..1] [184..284]
gi|50748592 - gi|50748592|ref|XP_421316.1| PREDICTED: similar to calmodulin 1; Calmodulin 1 (phosphorylase kinase,...
166.0 [0..18] [174..511]
gi|47221269 - gi|47221269|emb|CAG13205.1| unnamed protein product [Tetraodon nigroviridis]
166.0 [0..1] [184..1]
gi|66513911 - gi|66513911|ref|XP_392256.2| PREDICTED: similar to Neurocalcin homolog (DrosNCa) [Apis mellifera]
161.0 [0..1] [184..1]
gi|108880132, gi... - gi|157105260|ref|XP_001648788.1| hippocalcin [Aedes aegypti], gi|108880132|gb|EAT44357.1| hippocalci...
AGAP007247-PA, A... - Hippocalcin-like protein 1|protein_coding|2L:44619841:44628520:1|gene:AGAP007247, Hippocalcin-like p...
gi|170043833, gi... - gi|170043833|ref|XP_001849575.1| hippocalcin [Culex quinquefasciatus], gi|167867127|gb|EDS30510.1| h...
gi|158285993, gi... - gi|58376331|ref|XP_308553.2| ENSANGP00000015900 [Anopheles gambiae str. PEST], gi|55245634|gb|EAA041...
161.0 [0..1] [184..1]

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Predicted Domain #1
Region A:
Residues: [1-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKSQSKLSQ DQLQDLVRST RFDKKELQQW YKGFFKDCPS GHLNKSEFQK IYKQFFPFGD  60
   61 PSAFAEYVFN VFDADKNGYI DFKEFICALS VTSRGELNDK LIWAFQLYDL DNNGLISYDE 120
  121 MLRIVDAIYK MVGSMVKLPE DEDTPEKRVN KIFNMMDKNK DGQLTLEEFC EGSKRDPTIV 180
  181 SALSLYDGLV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.30103
Match: 1bjfA
Description: Neurocalcin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoprotein phosphatase activity 7.47426847861728 bayes_pls_golite062009
protein serine/threonine phosphatase activity 6.37104157544514 bayes_pls_golite062009
phosphatase activity 6.28157965296365 bayes_pls_golite062009
phosphoric ester hydrolase activity 6.17799259119197 bayes_pls_golite062009
calcium-dependent protein serine/threonine phosphatase activity 5.58369939851095 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 5.11186887221409 bayes_pls_golite062009
calcium-dependent protein serine/threonine phosphatase regulator activity 4.70715233640875 bayes_pls_golite062009
calcium ion binding 3.79609619542776 bayes_pls_golite062009
binding 3.17556402087346 bayes_pls_golite062009
cation binding 2.62077305565026 bayes_pls_golite062009
metal ion binding 2.62077305565026 bayes_pls_golite062009
ion binding 2.61312132078717 bayes_pls_golite062009
clathrin binding 2.36616108128297 bayes_pls_golite062009
protein binding 2.21291432166051 bayes_pls_golite062009
transcription regulator activity 1.9739523190593 bayes_pls_golite062009
cytoskeletal protein binding 1.6550001867465 bayes_pls_golite062009
DNA binding 1.55722307354604 bayes_pls_golite062009
nucleic acid binding 1.53225451586959 bayes_pls_golite062009
structural constituent of muscle 1.30577051923353 bayes_pls_golite062009
calcium-dependent protein kinase inhibitor activity 1.29632226581856 bayes_pls_golite062009
actin filament binding 1.25849450788569 bayes_pls_golite062009
actin binding 1.1967948958876 bayes_pls_golite062009
transporter activity 1.15928534291452 bayes_pls_golite062009
molecular transducer activity 1.11607939838219 bayes_pls_golite062009
signal transducer activity 1.11607939838219 bayes_pls_golite062009
transmembrane transporter activity 0.945691505472547 bayes_pls_golite062009
phosphatase regulator activity 0.87149881541475 bayes_pls_golite062009
motor activity 0.85125321350375 bayes_pls_golite062009
guanylate cyclase regulator activity 0.84389905735679 bayes_pls_golite062009
cyclase regulator activity 0.84389905735679 bayes_pls_golite062009
protein phosphatase regulator activity 0.822713961141111 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.787740261079819 bayes_pls_golite062009
kinase activity 0.782396352346639 bayes_pls_golite062009
calcium channel regulator activity 0.7164851905066 bayes_pls_golite062009
substrate-specific transporter activity 0.693724160233023 bayes_pls_golite062009
transcription repressor activity 0.666488715029225 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.654002071540024 bayes_pls_golite062009
calcium sensitive guanylate cyclase activator activity 0.630360514213104 bayes_pls_golite062009
microfilament motor activity 0.515693296786409 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.45412801027969 bayes_pls_golite062009
active transmembrane transporter activity 0.246383459363256 bayes_pls_golite062009
ion transmembrane transporter activity 0.193201281459889 bayes_pls_golite062009
structural molecule activity 0.048100972187449 bayes_pls_golite062009
cation transmembrane transporter activity 0.0305250212662123 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle