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Protein Overview: nas-31

General Information:
Name(s) found: nas-31 / CE35882 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00003549 locus:nas-31 Zinc metalloproteinase nas-31 status:Partially_confirmed UniProt:Q7JLI1 protein_id:CAE48502.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 611 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: proteolysis [IEALink to PubMed article]
    Molecular Function: meprin A activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    astacin activity [IEALink to PubMed article]
    metallopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILQLLFYSL FTHLAVSQID VNQALNQNKL NIDTISSSAI SDAELEKTFP RTNLSRMRNA  60
   61 LKSLRQNWSA KLQAMPARNY QNAGTNQENG ATEQQKPLRE KPRDRVKMEG DTLHQVNKAA 120
  121 GLNDILYQGD MVLTDDQIAT ILEARDETTV STASRARRQA YRDRYYPSTT WGSSVYYYYD 180
  181 RTATPKIVKA FEQAVAFWQN VTCINIMQSS TAINRIRVFK GQGCYSYVGR ISGVQDLSLG 240
  241 TGCEEFGTAA HELGHALGFF HTQSRYDRDN YISINYANID PSYVEQFDKE TSNTNFNYGM 300
  301 PYDYGSIMQY GATSASSNDK ATMIARDTEY QDTMGSDFVG FYDISMMNEH YKCKELCPAA 360
  361 SSAQCKNGGF PSPRNCAICI CPSGYGGILC DQRPPGCGDS VTATTTWQTL TNTIGDGLPT 420
  421 LRDNHTMCNY WVKAPDNQAV EIRISGLTTV TIDGCIFGGV EIKTHKDQKL TGYRYCSSAD 480
  481 QNTVHRSTGS LVPIILFNRY ASTKAVLEYR AVTPSVDVSA TYTTFAPIVN SCQDLHPNCD 540
  541 FYKFFGMCRS KKIRSNCKFT CHDCNNNNAS PFGSNFFNNN YNSFNNWYTN KNKNYYPYSN 600
  601 SNNNKPWMWF F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..123] deduced N/A No confident structure predictions are available.
    2 View Details [124..281] PSI-BLAST 35.69897 STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
    3 View Details [282..356] FFAS03 2.63 STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
    4 View Details [357..611] PSI-BLAST 26.69897 Mannose-binding protein associated serine protease 2, MASP2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.361128926739778 bayes_pls_golite062009
  • hydrolase activity
    		•  0.29183147920977 bayes_pls_golite062009
  • peptidase activity
    		•  0.23695590197447 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.0341081586881899 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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