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View Structure Prediction Details

Protein: nas-31
Organism: Caenorhabditis elegans
Length: 611 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-31.

Description E-value Query
Range
Subject
Range
nas-31 - zinc metalloprotease status:Partially_confirmed UniProt:Q7JLI1 protein_id:CAA98497.2
407.0 [0..1] [572..1]

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Predicted Domain #1
Region A:
Residues: [1-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILQLLFYSL FTHLAVSQID VNQALNQNKL NIDTISSSAI SDAELEKTFP RTNLSRMRNA  60
   61 LKSLRQNWSA KLQAMPARNY QNAGTNQENG ATEQQKPLRE KPRDRVKMEG DTLHQVNKAA 120
  121 GLN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [124-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DILYQGDMVL TDDQIATILE ARDETTVSTA SRARRQAYRD RYYPSTTWGS SVYYYYDRTA  60
   61 TPKIVKAFEQ AVAFWQNVTC INIMQSSTAI NRIRVFKGQG CYSYVGRISG VQDLSLGTGC 120
  121 EEFGTAAHEL GHALGFFHTQ SRYDRDNYIS INYANIDP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.69897
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.361128926739778 bayes_pls_golite062009
hydrolase activity 0.29183147920977 bayes_pls_golite062009
peptidase activity 0.23695590197447 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.0341081586881899 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [282-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYVEQFDKET SNTNFNYGMP YDYGSIMQYG ATSASSNDKA TMIARDTEYQ DTMGSDFVGF  60
   61 YDISMMNEHY KCKEL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.63
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [357-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CPAASSAQCK NGGFPSPRNC AICICPSGYG GILCDQRPPG CGDSVTATTT WQTLTNTIGD  60
   61 GLPTLRDNHT MCNYWVKAPD NQAVEIRISG LTTVTIDGCI FGGVEIKTHK DQKLTGYRYC 120
  121 SSADQNTVHR STGSLVPIIL FNRYASTKAV LEYRAVTPSV DVSATYTTFA PIVNSCQDLH 180
  181 PNCDFYKFFG MCRSKKIRSN CKFTCHDCNN NNASPFGSNF FNNNYNSFNN WYTNKNKNYY 240
  241 PYSNSNNNKP WMWFF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.69897
Match: 1nt0A
Description: Mannose-binding protein associated serine protease 2, MASP2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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